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c/sideeffects·posted 1 year ago by u/ilias_cabrera

help me understand nausea, I have read the wiki twice

PSA Cold Box ×1 Long Haul ×2 Receipts ×2

help me understand nausea, I have read the wiki twice. Searched first, found three threads that contradict each other, hence the post.

Held the dose for an extra six weeks instead of stepping. The sulphur burps settled and I lost the same amount anyway.

The fatigue turned out to be that I was eating about a third of what I thought I was. Tracked it for a week and the mystery evaporated.

On buying things to fix side effects, which I did extensively and would not do again.

The interventions that changed anything for me were all behavioural and free: smaller meals, eating slower, stopping food a few hours before sleep, more fibre and considerably more water. The things I bought did nothing I could detect, and I was motivated to detect something.

The other lever, which people forget, is time at dose. Holding rather than stepping is a legitimate plan and it fixed my tolerance where nothing else did.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

6,230 up / 1,286 down83% upvoted64 commentsid fex5vs20 Jun 2025

64 comments

27 in this archive, depth 5

best — the order this archive was captured in

u/iman_castellanos0 points·1 year ago

The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.

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u/enzo_danquah1 point·1 year ago

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

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u/yannick_barros1 point·1 year ago

Nothing in this thread is medical advice, including this comment.

This is the shape almost everybody here describes, and it is the single most reassuring thing in the thread.

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u/kavya_kravchenko2 points·1 year ago

Small fix — the shedding follows the rate of weight loss, not the compound, and it is temporary.

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u/plain_titration_20241 point·1 year ago·edited

smaller meals, earlier, is the boring advice that works

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u/zeynep_ndiaye1 point·1 year ago

reflux at night, try not eating in the three hours before bed

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u/placebo_arm_pam1 point·1 year ago

Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.

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u/ferran_krastev-24 points·1 year ago

How long after a step up did this start?

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u/food_noise_gonemaintenance0 points·1 year ago

Keeping a log, and what to put in it.

One line a day: dose, day since injection, what the symptom was and how bad out of five, and roughly what you ate. Two months of that fits on one page and the pattern is obvious on paper in a way it never is in your head.

Mine showed a clean day-two-to-day-four window I had been describing as "random". Once you can see the pattern you can plan around it, and planning around it is most of the relief.

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u/tomas_broberg434 points·1 year ago

Disagree. Severe abdominal pain is not on the list of things to wait out, and this board should not be treating it as one.

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u/fatima_asante299 points·1 year ago

hair shedding follows the weight loss, not the drug, and it stops

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u/blank_injection264 points·1 year ago

sulphur burps are unpleasant and they are not dangerous

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u/step_therapy_s166 points·1 year ago

Severe, or unpleasant? They are genuinely different questions and the answers diverge.

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u/constipation_clubMOD130 points·1 year ago

Left up. It is a description of one person’s week and it is flagged as such.

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u/enzo_danquah32 points·1 year ago

fibre and water before you buy anything to fix it

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u/ilias_cabreraOP19 points·1 year ago

What is intake actually looking like — fibre and water especially?

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u/adaeze_brandt109 points·1 year ago

Has anything else changed in the same window?

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u/food_noise_gonemaintenance56 points·1 year ago

I would be careful here. "Everyone gets this" is not true, and it makes the people who get something unusual assume they are fine when they should be asking.

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u/tl_dr_tina24 points·1 year ago

fatigue plus low intake is usually just low intake

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u/plain_titration_202481 points·1 year ago

Kept a one-line-a-day log for two months. The pattern was obvious on paper and invisible in my head.

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u/ilias_cabreraOP44 points·1 year ago

Which day of the week relative to the shot does it hit?

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u/aurel_mwangi13 points·1 year ago

eating slower does more than most of the supplements people recommend

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u/neha_rahimi4 points·1 year ago

holding a dose an extra month is a legitimate answer to bad tolerance

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u/thermal_mass_tom50 points·1 year ago

a rough fortnight at each step is normal, a rough three months is not

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u/cormac_danquah37 points·1 year ago

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

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u/ilias_cabreraOP29 points·1 year ago

Correcting my own comment above: I said day three and my log says day two. Same pattern, wrong day.

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u/aleksi_lehtinen14 points·1 year ago

Agreed. Slowing down at meals did more for my early fullness than everything I bought to fix it, which was embarrassing to discover.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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