[Discussion] reflux is doing more work than we give it credit for
reflux is doing more work than we give it credit for. It is the sort of thing everyone half-believes and nobody writes down.
The effect on gastric emptying is most pronounced early and attenuates with continued dosing, which is the mechanism behind the "it settles at a stable dose" pattern the whole board reports.
Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working.
Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.
Sceptical readings welcome. The confident ones are the ones I distrust.
best — the order this archive was captured in
Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.
if it is severe or persistent that is a clinician question, not a board question
That symptom is not the one being described upthread. Two different things with similar names and the answers are not interchangeable.
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Disagree. Severe abdominal pain is not on the list of things to wait out, and this board should not be treating it as one.
Small fix — the shedding follows the rate of weight loss, not the compound, and it is temporary.
This. A bad fortnight after a step is expected. A bad quarter is a reason to talk to somebody who knows your history.
the first fortnight after a step is the worst of it, then it settles
This.
Adding to this — holding the dose rather than stepping is the option people forget they have.
Correction: that is a known effect of reduced intake rather than a direct drug effect. The distinction matters because the fix is different.
fibre and water before you buy anything to fix it
Most of the common complaints trace back to slowed gastric emptying — early fullness, reflux, nausea after a large or fatty meal. That is also why meal size and speed change the experience more than anything else.
The fatigue turned out to be that I was eating about a third of what I thought I was. Tracked it for a week and the mystery evaporated.
holding a dose an extra month is a legitimate answer to bad tolerance
hair shedding follows the weight loss, not the drug, and it stops
This one needs a clinician rather than a comment section, and we have said so in the thread rather than removing it.
a rough fortnight at each step is normal, a rough three months is not
Not convinced by that mechanism. Slowed gastric emptying explains fullness and reflux; it does not explain what you are describing.
Are you eating in the couple of hours before you sleep?
write down when it starts and stops, the pattern is the useful part
Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.
- 1Severe or persistent abdominal pain sits outside the pattern this board can…10 comments in this branch · started by u/chidi_demir