tirzepatide

stalled for 18 weeks at 12.5mg and I refuse to panic this time — a position I have arrived at slowly and would like tested. To save the first four comments: 18 weeks…

Asking properly rather than in a comment on somebody else’s thread: why is nobody talking about the SURPASS-CVOT readout. Vials and pens carry the same molecule; what…

Question in the title, detail here: does the vial concentration change how much dead space costs me. The distribution matters more than the mean. In the trial…

Thinking out loud about this: we are measuring Zepbound at the wrong time and calling it noise. Went 10 to 12.5 on the calendar and had the worst fortnight of the whole…

genuine question about tirzepatide that I am slightly embarrassed to ask. If this has been answered properly somewhere, link me and I will delete. Research-use-only…

The claim in the title is exactly the claim I am making: is 99.3% actually fine or am I being sold a rounding error. Nothing implied beyond it. Pulling the figures out…

Result first, context after: 4th independent test on JEEP — 97.3% on a claimed 97.0%, and the trend is the interesting part . Everything below is how it was ordered,…

unpopular opinion: most of what gets said here about GIP is guesswork. Making the case below, and I expect to lose some of it in the comments. SURMOUNT-1 ran 72 weeks…

Right: SURMOUNT-1 was -20.9% at 72 weeks. that is the number, not -30%. I paid for this one myself, nobody sent me anything, and the receipts are in the comments. Hard…

how do you actually verify Zepbound. I am not trying to be the "source?" guy. I would just like a source. The step schedule question, answered properly, because it…

8th independent test on QST — 98.6% on a claimed 98.5%, and the trend is the interesting part. I will put the method line and the batch identifier up front because that…

Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about Mounjaro actually comes from Zepbound threads. On comparing…

Filing this under things worth writing down: split one vial across Medutest and Janoshik — 99.3% and 98.7%. To save the first four comments: 99.3% and 98.7%.…

nobody warned me about muscle cramps and I would have liked the warning. Change my mind, genuinely — I have no stake in being right about this. Switching from…

Slightly embarrassed to be asking this, but: how much of what we believe about Mounjaro actually comes from SURMOUNT threads. SURMOUNT-1 ran 72 weeks with the top arm…

Something I keep coming back to: SURPASS is doing more work than we give it credit for. Week 44 was the first time the scale moved after a five-week stall. I changed…

small win: Mounjaro stopped being a problem at week 66. Posting the boring middle of the process, because the internet is full of the start and the end and nothing…

Reporting in. is it normal to get food noise at week 85. Research-use-only material is not approved for human use. Anything in this thread about how a research vial…

"tirz is stronger than sema" needs a comparator dose or it means nothing. Making the case below, and I expect to lose some of it in the comments. Came off sema and onto…

is it normal to get constipation at week 87, and the part I actually want to talk about is at the bottom. Came off sema and onto tirz with a two-week gap. The first…

anyone else notice GIP kicking in around week 81, logged the same way every week so the comparison is at least internally fair. Sulphur burps for the first eight days…

Check-in as promised in the title: 65 weeks on 15mg, full numbers, ask me anything boring. The relevant figures are 65 weeks and 15mg, and they come from the same log I…

tirzepatide — 9 things I got wrong before I got it right. Change my mind, genuinely — I have no stake in being right about this. Switching from semaglutide, since three…

Check-in as promised in the title: is it normal to get muscle cramps at week 54. Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped…