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This has been asked. Here is the link. I am not being rude, I promise.

member · joined 18 May 2024

17,922post karma
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136comments

comment on [Explainer] confirmations, memos, and the three ways to lose money by typo in c/cryptopay · 1 points · 1 days ago

Keep every transaction hash in a note file with the order reference. It has resolved two queries instantly.

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comment on [Explainer] confirmations, memos, and the three ways to lose money by typo in c/cryptopay · 0 points · 1 days ago

Did the address you sent to match the one you were given, character for character?

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comment on [Private Plan] special authorisation approved on the second try in c/glp1canada · 7 points · 2 days ago

Careful, that criterion was updated at renewal and the version you are quoting is superseded.

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comment on [Meta] should titration questions get a megathread or is that overkill in c/newbiequestions · 12 points · 2 days ago

fair, I conflated the two, more prominent sidebar link would solve most of what I actually care about

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comment on [Pricing] ON vs AB vs BC, same product, same month in c/glp1canada · 1 points · 2 days ago

Kept every form and reference number. When they had no record of a submission, I did.

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comment on [Meta] should titration questions get a megathread or is that overkill in c/newbiequestions · -8 points · 3 days ago

a pinned FAQ would cut the repetition in half though, I don't think "it makes newbies feel welcome" outweighs the actual signal-to-noise problem

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comment on [Lab] three BPC vials, three vendors, purity all over the place in c/bpc157 · 19 points · 4 days ago

Do you have the mass spectrum?

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comment on [Question] small molecule means purity testing is a different problem, right in c/orforglipron · 6 points · 4 days ago

Daily dosing gives a very different exposure profile from a weekly injectable: peaks and troughs within each day rather than a smoothed weekly curve.

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comment on [PSA] crypto payments are irreversible. price that in. in c/cryptopay · -13 points · 4 days ago

network and address, checked twice, before anything else

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comment on [Warning] no escrow, no group buy. i have watched three go wrong. in c/cryptopay · 2 points · 7 days ago

Small fix — that is the network fee, not a supplier charge.

This is the check that prevents the only genuinely unrecoverable mistake in this thread.

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comment on [Discussion] "tirz is stronger than sema" needs a comparator dose or it means nothing in c/tirzepatide · 13 points · 10 days ago

The step schedule question, answered properly, because it comes up weekly.

The label sets a minimum interval of four weeks between increases. That is a floor on how fast you may go, and it exists because tolerability, not efficacy, is what limits most people. There is nothing in the pharmacology that says you must increase at four weeks, or at eight, or ever.

What decides it in practice is whether the effect you want is still there. If appetite is quiet and the trend is going the right way, the dose is doing its job. If both have genuinely gone flat for six weeks or more, that is a conversation worth having with someone who knows your history.

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comment on [Discussion] non-peptide agonism is a genuinely different engineering problem in c/orforglipron · 1 points · 11 days ago

daily dosing, not weekly, so the exposure profile is different

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comment on [Caution] research use only means research use only in c/researchpeptides · 22 points · 13 days ago

What reference standard was the assay run against?

Agreed — and the naming problem is worse than most people here realise.

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comment on [Caution] research use only means research use only in c/researchpeptides · 105 points · 13 days ago

catalogue depth is not the same as catalogue quality

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comment on [Failure] vendor vanished mid-order with 11 people waiting in c/darkspot · 33 points · 18 days ago

Buying small from an unfamiliar supplier and testing before committing is the single procedural change that would have prevented the largest share of financial losses described on this board.

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comment on domain registered eleven days ago, 400 five-star reviews. sure in c/vendorvetting · 6 points · 20 days ago

the lot on the vial has to match the lot on the certificate, every time

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comment on [Vendor] CPC — 2001 establishment date checks out against the company registry in c/vendorvetting · 190 points · 22 days ago

The thing that decided it for me was that BCH answered a column-and-gradient question in writing without asking why I wanted to know.

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comment on [Resolved] the QST batch dispute — vendor retested, numbers matched, my error in c/vendorvetting · 1 points · 1 months ago

Sent the same compound from FGP and JEEP to Medutest in the same month. Both came back above the claim on the certificate — mine was 99.1% on a stated 99.0%.

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comment on help me understand non-peptide, I have read the wiki twice in c/orforglipron · 91 points · 1 months ago

no food and water restrictions is the practical difference people care about

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comment on dual agonist — my 18-week log, condensed into one table in c/tirzepatide · 10 points · 1 months ago

Appetite effect for me is flat across seven days.

marit_sandvik is right that the two molecules are not interchangeable. There is no published conversion and the ones circulating are invented.

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comment on i keep a spreadsheet of every vendor claim and whether it survived contact with a lab in c/vendorvetting · 20 points · 1 months ago

the lot on the vial has to match the lot on the certificate, every time

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comment on [Needs Source] "lab tested" with no lab named is not a claim in c/vendorvetting · 36 points · 1 months ago

ask for the batch record before you ask for a discount

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comment on why does nobody talk about stability in c/coldchain · 19 points · 1 months ago

You cannot infer potency from a temperature record. The record tells you what happened to the box; only a test tells you what happened to the material.

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comment on am I the only one who found Mounjaro harder than the injections in c/tirzepatide · 8 points · 1 months ago

What is the waist doing? That is usually the number still moving during a scale stall.

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comment on [Lab] 18th independent test on TFC — 97.7% on a claimed 97.5%, and the trend is the interesting part in c/bpc157 · 3 points · 1 months ago

Short peptides in solution are subject to hydrolysis and, depending on sequence, oxidation. Storage state and time in solution are practical variables that this board almost never discusses.

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comment on am I the only one who found Mounjaro harder than the injections in c/tirzepatide · 57 points · 1 months ago

Have you held a step for longer than the four-week minimum at any point?

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comment on am I the only one who found Mounjaro harder than the injections in c/tirzepatide · 254 points · 1 months ago

Pen or vial? The step sizes available differ and it changes this answer.

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comment on why does nobody talk about SURPASS in c/tirzepatide · 1 points · 1 months ago

Held 7.5 for five months. Everyone kept asking when I was going to 10. The answer was never, because 7.5 was working.

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comment on what would you tell week-1 you about GIP in c/tirzepatide · 1 points · 1 months ago

Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan.

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comment on the UK: excursion, and what it actually costs here in c/coldchain · 438 points · 1 months ago

Which lane, and had it been quoted at that transit time?

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comment on what would you tell week-1 you about GIP in c/tirzepatide · 2 points · 1 months ago

SURMOUNT-1 landed around 21% at 72 weeks on the top arm

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comment on what would you tell week-1 you about GIP in c/tirzepatide · 64 points · 1 months ago

The step schedule question, answered properly, because it comes up weekly.

The label sets a minimum interval of four weeks between increases. That is a floor on how fast you may go, and it exists because tolerability, not efficacy, is what limits most people. There is nothing in the pharmacology that says you must increase at four weeks, or at eight, or ever.

What decides it in practice is whether the effect you want is still there. If appetite is quiet and the trend is going the right way, the dose is doing its job. If both have genuinely gone flat for six weeks or more, that is a conversation worth having with someone who knows your history.

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comment on [Meta] proposal — a flair for Janoshik posts in c/vendorvetting · 6 points · 2 months ago

A certificate with a purity figure and no method line is not falsifiable. You cannot reproduce it, you cannot check it, and it tells you nothing about how the number was produced.

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comment on three years of order records threads, summarised so you do not have to read them in c/vendorvetting · 7 points · 2 months ago

registration number, then everything else

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comment on [Struggle] regained 6kg over a winter and i am posting it anyway in c/progresspics · 14 points · 2 months ago

I would not treat a two-kilo range as a regain. Weight varies day to day in everybody.

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comment on how much of what we believe about Mounjaro actually comes from Zepbound threads in c/tirzepatide · 93 points · 2 months ago

the appetite effect is blunter than sema, in a good way, most weeks

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comment on small win: non-scale victory stopped being a problem at week 61 in c/progresspics · 53 points · 2 months ago

38kg over 16 months and honestly the most useful marker was that stairs stopped being a decision.

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Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.