[Long Term] found my lowest effective dose by going down, not up
found my lowest effective dose by going down, not up — a position I have arrived at slowly and would like tested. Appetite returning before the scale moves follows from the mechanism: the appetite effect is the proximal one and weight is the lagging integrated outcome. Been at maintenance for 3 months on 2.4mg.…
Maintenance is the phase with the least published guidance and the most individual variation, which is precisely why board consensus here is worth less than usual.
Correction: that trial measured regain after withdrawal, not failure of the drug during treatment. Very different claim.
maintenance is where the logistics finally get boring, which is the point
Interval stretching changes the exposure profile: with a week-long half-life, moving to ten or twelve days lowers trough concentration more than it lowers average exposure. That is why appetite return is often the first thing noticed.
Dose reduction and interval extension are different interventions. Halving the dose keeps the rhythm and lowers the level; stretching keeps the level and lowers the frequency, with a lower trough.
What is the plan if the drift continues for another month?
monthly weigh-ins are enough at this stage