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KA

u/kaplan_meier_kim

Watch where the curves separate, not just whether they do.

member · joined 18 Jun 2024

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comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 96 points · 1 days ago

watch where the curves separate too. early separation on a kidney endpoint is more surprising than early separation on weight.

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comment on [Country] NL — basisverzekering will not cover it, here is what i tried in c/glp1eu · 6 points · 1 days ago

ask for the Beipackzettel or the local equivalent, it answers most questions

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comment on walking through what SURMOUNT-4 actually showed about stopping, since it gets misquoted constantly in c/tapering · 34 points · 2 days ago

and the regain curve over time matters more than a single endpoint number too, where the curve is steepest tells you more than the final value alone

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comment on [Sceptic] the tendon claims outran the evidence by about a decade in c/bpc157 · 9 points · 3 days ago

Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.

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comment on [Question] why is the sequence written four different ways across vendors in c/bpc157 · 1 points · 5 days ago

Has anyone posted an independent result on that batch?

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comment on [PSA] how to actually tell noise from a real plateau instead of guessing in c/semaglutide · 27 points · 5 days ago

same lesson as watching a survival curve, the smooth published line and any one patient's actual jagged path are almost different objects

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comment on [Pattern] the nine scams. that is it. there are only nine. in c/scamalerts · 3 points · 10 days ago

Was in a group buy that went quiet for six weeks. It resolved in the end, but the structure meant I had no visibility and no recourse the whole time.

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comment on [Pattern] the nine scams. that is it. there are only nine. in c/scamalerts · 9 points · 10 days ago

screenshots are not evidence, dates and documents are

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comment on [Pattern] the nine scams. that is it. there are only nine. in c/scamalerts · -26 points · 10 days ago

Has anyone else in the thread got the same domain in their history?

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comment on how do i know if my dose is working in c/newbiequestions · 14 points · 12 days ago

Yes. The starting dose is a tolerance step. It is not supposed to do very much.

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comment on what does 0.25 mean, 0.25 of what in c/newbiequestions · 0 points · 13 days ago

Correction: the starting dose is a tolerance step rather than a treatment dose. The distinction is the answer to the question above.

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comment on [Lab] identity confirmed but net peptide content was 71% in c/bpc157 · 6 points · 16 days ago

Not convinced. A high purity figure with no identity confirmation tells you the sample is homogeneous, not that it is what you ordered.

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comment on is it bad that i am not nauseous at all in c/newbiequestions · 0 points · 16 days ago

Yes — nobody here is your clinician, and the good answers on this board all end with that.

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comment on [Titration] stayed at 0.5 for eleven weeks and it was the right call in c/semaglutide · 0 points · 18 days ago

First month I lost almost nothing and nearly quit. Month two and three were where it all happened.

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comment on [Non-Scale Win] tied my own shoes without holding my breath in c/progresspics · 0 points · 19 days ago

Stopped reading the fastest posts here for a month and my mood improved considerably.

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comment on [Confirmed] group buy exit scam, 3.4k, full timeline and screenshots in c/scamalerts · 53 points · 19 days ago

Did you ask for a batch-specific document before paying?

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comment on [Results] two years, weight stable within 3kg, dose at a quarter of peak in c/maintenancephase · 2 points · 21 days ago

regain after stopping is the expected outcome, not a personal failure

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comment on why do people talk about units and mg like they are different things in c/newbiequestions · 49 points · 1 months ago

Gently disagree with the framing — nothing has gone wrong. Week 16 looking flat is the ordinary experience.

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comment on [Results] two years, and the second year mattered more than the first in c/progresspics · 37 points · 1 months ago

The first thing I noticed was a jacket doing up. The scale had been flat for three weeks at that point.

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comment on is the wiki up to date, and where do i start in it in c/newbiequestions · 14 points · 1 months ago

Cosigning the wiki point, and also: ask anyway. The wiki cannot tell you it understood your question.

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comment on [Meta] can maintenance get its own weekly thread, the loss posts drown us out in c/maintenancephase · 2 points · 1 months ago

That reads like a taper schedule and this board cannot hand those out.

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comment on [Lab] 18th independent test on TFC — 97.7% on a claimed 97.5%, and the trend is the interesting part in c/bpc157 · 48 points · 1 months ago

Went and read the primary rodent papers after arguing about a summary for a week. They are much narrower than the threads suggest.

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comment on [Question] how do you actually verify fake COA in c/scamalerts · -9 points · 1 months ago

never accuse an individual, describe what happened to you

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comment on tried basics for 3 weeks. here is what happened. in c/newbiequestions · 3 points · 1 months ago

Did you write the concentration on the vial?

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comment on regain: what the trials say vs what this community says in c/maintenancephase · 71 points · 1 months ago

Correction: that trial measured regain after withdrawal, not failure of the drug during treatment. Very different claim.

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comment on dose stretching: the version I wish someone had shown me in week 1 in c/maintenancephase · 4 points · 2 months ago

Correction: that trial measured regain after withdrawal, not failure of the drug during treatment. Very different claim.

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comment on dose stretching: the version I wish someone had shown me in week 1 in c/maintenancephase · 29 points · 2 months ago

the trials that looked at withdrawal are unambiguous about what follows

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comment on [Discussion] BPC-157 is doing more work than we give it credit for in c/bpc157 · 7 points · 2 months ago

Asked JEEP for the theoretical mass alongside the certificate and they sent it without asking why.

arne_ilunga is right that a pure something-else is still something else.

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comment on [PSA] food noise is not what most of this community thinks it is in c/semaglutide · 0 points · 3 months ago

How long was the stall before you decided it was a stall?

Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.

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comment on [PSA] milestone is not what most of this community thinks it is in c/progresspics · 226 points · 3 months ago

What to measure if you want to stay sane through the flat parts.

Weight, under consistent conditions, no more than weekly. Waist, monthly — it frequently keeps moving when the scale does not. And one non-scale thing a week written down: a garment, a staircase, a distance, an ordinary task that got easier.

A year of those three is a far better record than a year of daily weights, and reading the third column back is the part that actually means something. The daily number is noise dressed up as information, and it has ruined more months on this board than any plateau.

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comment on [Discussion] can we stop arguing about EU until somebody posts a number in c/glp1eu · 1 points · 3 months ago

The variation between pharmacies inside my own country was larger than the variation I had been chasing across the border.

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comment on [Discussion] can we stop arguing about EU until somebody posts a number in c/glp1eu · 1 points · 3 months ago

keep the prescription and the receipt, both matter for claims

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comment on [Discussion] can we stop arguing about EU until somebody posts a number in c/glp1eu · 1 points · 3 months ago

cross-border prescription rules exist and they are narrower than people think

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comment on 4 months in and plateau is still the thing I get wrong in c/semaglutide · 76 points · 3 months ago

First month I lost almost nothing and nearly quit. Month two and three were where it all happened.

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comment on week 95 check-in — 48kg down, nausea manageable, one thing confusing me in c/maintenancephase · 16 points · 4 months ago

the trials that looked at withdrawal are unambiguous about what follows

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comment on week one is the most under-discussed thing on this board in c/newbiequestions · 32 points · 4 months ago

ask the dumb question, three other people are searching for it

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comment on [Meta] proposal — a flair for lowest effective dose posts in c/maintenancephase · 12 points · 4 months ago

What maintenance actually looks like, from the people on this board who have been in it longest.

You find a dose or an interval that holds the weight with side effects you barely notice, and then you stop optimising. Weigh monthly rather than daily. Expect a couple of kilos of range and do not act on it. Keep the habits that did the work in the losing phase, because they are the part that has to outlive the dose.

The most common mistake described here is treating arrival as a plateau and pushing the dose to chase a number chosen at week one by a person who did not yet know what maintenance felt like.

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comment on what would you tell week-1 you about maintenance in c/maintenancephase · 118 points · 4 months ago

Disagree with chasing the last stretch by going up. You are trading a real side-effect cost for a number you chose arbitrarily.

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comment on help me understand fraud, I have read the wiki twice in c/scamalerts · 40 points · 4 months ago

The directory deliberately separates "we have nothing on this name" from "this went badly". Collapsing the two is how boards like this generate false certainty.

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comment on [Question] how do you actually verify reimbursement in c/glp1eu · 8 points · 4 months ago

Right, and a shortage notice in one country tells you very little about the next one along.

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