280
19 months at maintenance. the interesting part starts after the loss stops.
19 months at maintenance. the interesting part starts after the loss stops. Not a hot take, just something I have not seen said plainly here. The relevant figures are…
long term
Every GLP Research Hub submission tagged to long term, ranked by score. Discussed in 1 community.
Communities covering this
262
genuine question about maintenance that I am slightly embarrassed to ask
genuine question about maintenance that I am slightly embarrassed to ask. I would rather ask a basic question now than get this wrong quietly for two months. Interval…
183
[Discussion] the lowest effective dose advice in here is 2 years out of date
the lowest effective dose advice in here is 2 years out of date. I have gone back and forth on this for months. Hard numbers: 2 years. Anything softer than that is…
174
tapered slowly over four months instead of stopping cold, regain was 4kg not 24
Coming off deliberately after 22 months, worked with my prescriber on a gradual step-down over about four months rather than just stopping. One year post-taper:…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards164
someone explain regain to me like I have not read a paper in years
someone explain regain to me like I have not read a paper in years. Searched first, found three threads that contradict each other, hence the post. The habits from the…
161
[Question] do you tell new people how long this actually is
do you tell new people how long this actually is, and I want the answer with the reasoning attached rather than just the conclusion. Chased the last three kilos with a…
139
small win: maintenance stopped being a problem at week 92
Update, and the title has the headline: small win: maintenance stopped being a problem at week 92. Interval stretching changes the exposure profile: with a week-long…
135
[Meta] should this community rename "maintenance phase" to something that doesn’t sound like an afterthought
Half-serious, half-not. "Maintenance phase" as a name kind of implies it's the boring bit after the real thing happened. Reading enough threads here has convinced me…
107
went up a dose over a stall that turned out to be dehydration, learned an expensive lesson
Following up on my six-week-stall post from a while back. Went up. Two rough weeks of side effects. Scale moved... and then it turned out a chunk of the "movement" was…
103
[Question] does anyone actually feel "done" or is that not a thing
does anyone actually feel "done" or is that not a thing — that is what I am asking, and I have already read the wiki twice. The two levers, described properly, because…
97
[Meta] proposal — a flair for lowest effective dose posts
proposal — a flair for lowest effective dose posts. Short post, long comment section, probably. Withdrawal studies in this class consistently show substantial regain…
90
unpopular opinion: most of what gets said here about lowest effective dose is guesswork
unpopular opinion: most of what gets said here about lowest effective dose is guesswork. Making the case below, and I expect to lose some of it in the comments.…
78
nobody warned me about the identity gap once the thing that organized your life for a year is just... gone
For over a year, "losing weight" was a structuring project. Tracked, planned, celebrated milestones, had a clear direction. Hit goal, and there's genuinely a weird flat…
0
has anyone actually found their floor — the lowest dose that still holds the line
19 months in, at goal for about seven of those. Been slowly working with my prescriber to see how low I can go and still hold steady rather than just staying on…
0
six weeks flat at my top dose, is going up even an option at this point or just a bad idea
Been at my current dose for four months, first three months of steady loss then six weeks completely flat. Rolling average and all. Not panicking this time (learned…
Janoshik Analytical — independent HPLC & mass spec
Send the vial, get the number. Third-party purity and identity testing, results published to you regardless of what they say.
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Est. 1998. ISO 9001 and cGMP, 1,500+ staff, 200+ patents. There is a fair chance the vial you are about to send for testing started here. Batch-specific COA as standard.
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[Meta] can maintenance get its own weekly thread, the loss posts drown us out
can maintenance get its own weekly thread, the loss posts drown us out. Comments open, and the wording is genuinely up for discussion. Two years at maintenance. The…
0
the long term question that gets asked weekly, answered properly
the long term question that gets asked weekly, answered properly, and I am aware this is a minority view on this board. What maintenance actually looks like, from the…
-2
three years of dose stretching threads, summarised so you do not have to read them
three years of dose stretching threads, summarised so you do not have to read them. Making the case below, and I expect to lose some of it in the comments. Two years at…
-10
[Meta] the regain rule is doing its job and people should stop complaining
Housekeeping: the regain rule is doing its job and people should stop complaining. The two levers, described properly, because this board mixes them up constantly.…
-44
[Meta] proposal — a flair for maintenance posts
proposal — a flair for maintenance posts, and it will stay as it is unless somebody makes the case to change it. What maintenance actually looks like, from the people…