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Single comment threadYou are looking at one branch of [Question] how do you actually verify Mounjaro — 34 comments in the full submission. View in context.
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c/tirzepatide·submitted 1 year ago by u/line_petrov

[Question] how do you actually verify Mounjaro

Questionbranch of 9 comments

Asking properly rather than in a comment on somebody else’s thread: how do you actually verify Mounjaro. On comparing yourself with the trial number. SURMOUNT-1 reported roughly 21% mean body weight change at 72 weeks on the highest arm. Three things get dropped every time that figure is quoted here. It is a mean,…

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9 comments, started 1 year ago
u/titration_marshalMOD380 points·1 year ago

Left up, flair changed to Discussion. It is an opinion post and that is fine as long as it is labelled.

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u/line_petrov166 points·1 year ago

hold the dose that works, the ladder is not a leaderboard

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u/blunt_coldbox2947 points·1 year ago

That percentage is body weight change, not body fat. Different measurement, and the distinction gets lost every time.

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u/aurel_lindqvist21 points·1 year ago

pens and vials are the same molecule, the price is the difference

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u/customs_seizure_sid9 points·1 year ago

Week 7 was the first time the scale moved after a five-week stall. I changed nothing in that window.

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u/search_before_post271 points·1 year ago

the trials titrated on a calendar, real people titrate on symptoms

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u/adnan_nascimento189 points·1 year ago

dual agonist, so the GIP arm is doing something the sema threads will not tell you about

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u/ingrid_correia266 points·1 year ago

Left up, flair changed to Discussion.

Saving this one. It is the clearest statement of the stall problem I have read here.

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u/ferran_mensah309 points·1 year ago

Agreed, and the trial number is a mean of a very wide distribution — the tails are enormous and nobody posts from the middle.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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