unpopular opinion: most of what gets said here about MASH is guesswork. It is the sort of thing everyone half-believes and nobody writes down. Asked here what the…
c/survodutide — hot, page 2
Positions 26–50 of 62.
Short version of the title, which is already short: 24th independent test on QSC — 98.4% on a claimed 98.0%, and the trend is the interesting part. Longer version…
dual agonist is the most under-discussed thing on this board. I have gone back and forth on this for months. Phase 2 in a biopsy-confirmed population is a demanding…
dual agonist — 21 things I got wrong before I got it right, and I am aware this is a minority view on this board. What this compound is actually being developed for,…
PeptideMeter — community peptide analytics
Vendor-level purity averages over time, built from independent results rather than vendor claims. Transparent methodology, open dataset.
Browse resultsSlightly embarrassed to be asking this, but: someone explain biopsy to me like I have not read a paper in years. Bought small because the evidence base is early. That…
hepatic fat: the version I wish someone had shown me in week 1. Full detail below, and I have tried to keep the editorialising out of it. Bought small because the…
Check-in as promised in the title: small win: hepatic fat stopped being a problem at week 91. Nothing containing this compound is approved anywhere. Research-use-only…
Something I keep coming back to: my ALT moved and I cannot work out whether dual agonist is why. Imaging-derived liver fat fraction is a surrogate. It correlates with…
MASH is doing more work than we give it credit for. Change my mind, genuinely — I have no stake in being right about this. Spent an evening on the histology scoring…
28 weeks on 10mg, full numbers, ask me anything boring. This is a description of what happened to me and not a plan for anybody else. Numbers, in the order they matter:…
genuine question about MASH that I am slightly embarrassed to ask. I would rather ask a basic question now than get this wrong quietly for two months. Asked here what…
Asking properly rather than in a comment on somebody else’s thread: how do you actually verify biopsy. Went slowly because everything published describes a deliberate…
Something I keep coming back to: the biopsy question that gets asked weekly, answered properly. Sent a vial to Janoshik because there was nothing on file. 99.4% against…
Thinking out loud about this: three years of MASH threads, summarised so you do not have to read them. Spent an evening on the histology scoring system and understood…
small win: MASH stopped being a problem at week 43. Full detail below, and I have tried to keep the editorialising out of it. Imaging-derived liver fat fraction is a…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards4 months in and hepatic fat is still the thing I get wrong, logged the same way every week so the comparison is at least internally fair. The numbers the title…
Slightly embarrassed to be asking this, but: genuine question about dual agonist that I am slightly embarrassed to ask. Imaging-derived liver fat fraction is a…
Check-in as promised in the title: is it normal to get muscle cramps at week 88. Nothing containing this compound is approved anywhere. Research-use-only material is…
Posting this as a discussion rather than a claim: hepatic fat — 19 things I got wrong before I got it right. Went slowly because everything published describes a…
Homopeptide survo — Medutest came back 98.4% against a claimed 98.0%. One vial, one service, one member paying, which is the only kind of result this board should treat…
4 months in and MASH is still the thing I get wrong. Numbers below. Ask me the boring questions, they are the useful ones. Numbers, in the order they matter: 4 months.…
what changed for me between month 5 and month 8. I am not trying to be the "source?" guy. I would just like a source. Assumed the weight numbers were the point and was…
WWB survo — Medutest came back 99.2% against a claimed 98.5%. One vial, one service, one member paying, which is the only kind of result this board should treat as…
Trying to get a straight answer on this: why does nobody talk about survodutide. Went slowly because everything published describes a deliberate escalation. That is the…
reading MASH threads from 2024 and half of it aged badly. It is the sort of thing everyone half-believes and nobody writes down. Histological endpoints in this field…