Thinking out loud about this: phase 2 biopsy endpoints, and what "resolution" means. The honest evidence position, written out so this board does not drift. Phase 2…
Survodutide
c/survodutide · created 14 Feb 2024
GLP-1/glucagon dual agonist. MASH data and the hepatic angle.
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The phase 2 MASH results ( NEJM , 2024) are, to me, the most underdiscussed thing in this whole space. Biopsy-confirmed endpoints. Not an ALT screenshot, not imaging,…
survodutide MASH data is the most interesting hepatic readout in the class. Change my mind, genuinely — I have no stake in being right about this. Nothing containing…
Something I keep coming back to: glucagon co-agonism has its own safety story, stop generalising from tirz. Bought small because the evidence base is early. That is the…
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Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
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