GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of anyone else notice glucagon kicking in around week 51 — 32 comments in the full submission. View in context.
2.6k
c/retatrutide·submitted 2 months ago by u/deleted_my_history

anyone else notice glucagon kicking in around week 51

Cautionbranch of 9 comments

Check-in as promised in the title: anyone else notice glucagon kicking in around week 51. Nothing containing this compound is approved anywhere. Research-use-only material is not approved for human use, and that is a statement of fact rather than a disclaimer. Independent purity testing on this compound is thin…

Read the full submission and all 32 comments →

This branch

9 comments, started 2 months ago
u/emil_agyeman0 points·2 months ago

Glucagon receptor agonism is associated with increased energy expenditure and with hepatic effects. That is a mechanistic story with strong preclinical support and limited phase 2 human data.

replysharereportpermalink
u/andres_sorensen1 point·2 months ago

Has anyone posted an independent test on this compound recently?

replysharereportpermalink
u/matias_falk1 point·2 months ago

wait for phase 3 before you argue about rankings

replysharereportpermalink
u/farid_molnar1 point·2 months ago

dose escalation in the trials was slow for a reason

replysharereportpermalink
u/crosspost_bot_no1 point·2 months ago

Correction: TRIUMPH is the phase 3 programme. The number you are quoting is from the phase 2 readout, which is a different trial.

replysharereportpermalink
u/sofia_wikstrom1 point·2 months ago

nothing here is available as a prescription product, so read every thread with that in mind

replysharereportpermalink
u/heart_rate_bump1 point·2 months ago

heart rate is the thing people report watching

replysharereportpermalink
[removed]1 point·2 months ago

[removed by moderator]

replysharereportpermalink
u/deleted_my_historyOP1 point·2 months ago

That is body weight change, not fat mass. The trials report the first and people quote it as the second.

replysharereportpermalink

← back to the whole thread

About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

65kmembers
130submissions
Sep 2023created
submissions / month, last year
Sponsored

PeptideMeter Analytics

Independent testing plus vendor-level trend data. Community-funded, unaffiliated.

peptidemeter.com
More in c/retatrutide
c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/reta_and_regretu/trialwatch_theou/incretin_ivyu/ledger_mod
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →