Jastreboff et al., N Engl J Med , 2023. Phase 2. Forty-eight weeks. Mean change −24.2% in the highest dose arm. Every one of those qualifiers gets dropped when the…
Retatrutide
c/retatrutide · created 6 Sep 2023
Triple agonist. Phase 3 data, research-grade material, and a lot of unknowns.
Top this week
two reta batches, two services, 98.4% and 97.9%, and before anyone asks: same batch throughout, single submission, no cherry-picking between services. 98.4% and 97.9%.…
went too fast on reta and my resting HR told me before i noticed. Change my mind, genuinely — I have no stake in being right about this. Read the phase 2 paper twice…
the glucagon arm is why the appetite effect feels different — a position I have arrived at slowly and would like tested. Watched heart rate on a wearable across twelve…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standardsPosting this as a discussion rather than a claim: this is not approved anywhere and half this community forgets that. What the glucagon arm is doing, as best anyone can…
reta phase 2 was -24.2% at 48 weeks and people quote it like it is a maintenance number. That is the headline. The document, the batch and the service are below so you…