u/ms_fragmenter
Fragment ions do not care about your marketing copy.
member · joined 15 Jan 2025
Comments — page 3 of 3
comment on [Meta] the private prescription rule is doing its job and people should stop complaining in c/glp1uk · 53 points · 1 year ago
Discharge at goal, which nobody warns people about.
Specialist services in England are commissioned to deliver a defined intervention. Reaching goal is a successful outcome and it typically ends with discharge back to primary care. Whether prescribing continues after that is a local decision that varies, and plenty of members here have discovered it at the point of discharge rather than at the start.
The useful thing to do is ask early: what happens when I finish, and does prescribing continue in primary care in this area. Ask it in writing, keep the answer, and you will at least know which conversation you are heading for.
comment on help me understand lyophilised, I have read the wiki twice in c/coldchain · 22 points · 1 year ago
write the reconstitution date on the vial
comment on reading co-agonism threads from 2024 and half of it aged badly in c/cagrilintide · 188 points · 1 year ago
That is preclinical work and the thread is treating it as a human finding.
comment on help me understand lyophilised, I have read the wiki twice in c/coldchain · 27 points · 1 year ago
Which lane, and had it been quoted at that transit time?
comment on sequence — 10 things I got wrong before I got it right in c/bpc157 · 26 points · 1 year ago
Right, and regulatory status has genuinely moved in several jurisdictions. Answers from three years ago may be wrong now.
comment on the NHS thing finally clicked for me and I want to write it down in c/glp1uk · 10 points · 1 year ago
That is the first-month offer price, not the ongoing monthly cost. The tracker records the second one.
comment on CagriSema: the version I wish someone had shown me in week 1 in c/cagrilintide · 72 points · 1 year ago
Correction: that is the combination programme, not the monotherapy readout. Different arms, different numbers.
comment on [Question] Australia — has anyone got a straight answer on confirmations in c/cryptopay · 1 points · 1 year ago
Right, and confirmations are the status. "Sent" means nothing until the chain agrees.
comment on genuine question about gas fees that I am slightly embarrassed to ask in c/cryptopay · 260 points · 1 year ago
Escrow is not standard in this space. Wanting it is reasonable; expecting it as default is not.
comment on [Question] how do you actually verify SURPASS in c/trialwatch · 15 points · 1 year ago
phase 2 finds a dose, phase 3 measures the effect
comment on does SELECT actually matter or is it forum lore at this point in c/trialwatch · 44 points · 1 year ago
Correction: SURMOUNT is the obesity programme and SURPASS is the diabetes one. The figure you quoted belongs to the other one.
comment on three years of beginner threads, summarised so you do not have to read them in c/newbiequestions · 41 points · 1 year ago
the first month is a tolerance check, not a results phase
comment on three years of beginner threads, summarised so you do not have to read them in c/newbiequestions · 101 points · 1 year ago
Pen or vial?
comment on three years of beginner threads, summarised so you do not have to read them in c/newbiequestions · 50 points · 1 year ago
Is this your first step up or the starting dose?
comment on help me understand SURMOUNT, I have read the wiki twice in c/trialwatch · -17 points · 1 year ago
Read a press release and the publication three months apart. The hedging in the second one was substantial.
comment on [Discussion] private prescription is doing more work than we give it credit for in c/glp1uk · 143 points · 1 year ago
Four pharmacies, four prices, same product, same month. The spread was larger than I expected and none of them were the headline offer.
comment on the first time thing finally clicked for me and I want to write it down in c/newbiequestions · 6 points · 1 year ago
a COA is a certificate of analysis, the lab document for a batch
comment on [Discussion] the chargeback advice in here is 3 years out of date in c/cryptopay · 11 points · 1 year ago
nobody legitimate needs the payment in the next ten minutes
comment on dose history — my 20-week log, condensed into one table in c/dosinglogs · 30 points · 1 year ago
Annotation is what makes a log survive contact with your future self. A single note beside an unusual week saves an hour of puzzled reconstruction later.
comment on hazard ratio is the most under-discussed thing on this board in c/trialwatch · 44 points · 1 year ago
Open-label extensions lose their randomisation. Anybody still enrolled at week 104 is a selected group and the numbers describe that group.
comment on [Question] how do you actually verify USDC in c/cryptopay · 34 points · 1 year ago
match the address character by character, or paste and verify
comment on [Meta] the week one rule is doing its job and people should stop complaining in c/newbiequestions · 10 points · 1 year ago
Bacteriostatic water contains a preservative, which is what makes repeated entry into a vial reasonable. Sterile water does not, and the two are not interchangeable for that purpose.
comment on [Meta] the regulatory rule is doing its job and people should stop complaining in c/bpc157 · 23 points · 2 years ago
research-use-only means not approved for human use, and here that covers everything
marit_sandvik is right that a pure something-else is still something else.
comment on [Vendor] JEEP order #6 — Ireland, 13 days, no drama, receipts inside in c/coldchain · 4 points · 2 years ago
Asked ERP which lines they hold regionally and got a straight list back. That answered my summer ordering question completely.
comment on am I the only one who found amylin harder than the injections in c/cagrilintide · 46 points · 2 years ago
Complementary mechanisms are the rationale for pairing: satiety signalling alongside incretin signalling, rather than more agonism at the same recepto
Disagreeing with this line: that figure is from a combination arm and is being quoted as monotherapy.
comment on how much of what we believe about weekly update actually comes from tracking threads in c/dosinglogs · 10 points · 2 years ago
Logged the missed weeks as blanks rather than skipping them. The gaps turned out to be the informative part.
comment on someone explain pentadecapeptide to me like I have not read a paper in years in c/bpc157 · 0 points · 2 years ago
a fifteen-residue peptide is easy to make and easy to make badly
zaid_eriksen is right that a pure something-else is still something else.
comment on genuine question about TRIUMPH that I am slightly embarrassed to ask in c/trialwatch · 10 points · 2 years ago
That is a relative risk reduction. Quoting it without the absolute numbers overstates the case considerably.
comment on genuine question about TRIUMPH that I am slightly embarrassed to ask in c/trialwatch · 47 points · 2 years ago
Compared myself to a trial mean for about six months before realising the trial arm had dietitian contact every fortnight.
comment on small win: what is stopped being a problem at week 72 in c/newbiequestions · 50 points · 2 years ago
Careful — that is a dosing recommendation dressed as an anecdote, and this board removes those.
comment on [Discussion] can we stop arguing about network until somebody posts a number in c/cryptopay · 79 points · 2 years ago
Same. Asking which networks are accepted before ordering has saved me twice.
comment on week 68 check-in — 34kg down, nausea manageable, one thing confusing me in c/cagrilintide · 11 points · 2 years ago
do not assume the dosing intuitions from the GLP-1 boards transfer
plain_titration is right that the evidence base here is thin. Conclusions should be held loosely.
comment on the pricing thing finally clicked for me and I want to write it down in c/glp1uk · 13 points · 2 years ago
Which pharmacy, and what did they quote for the month rather than the first month?
comment on [Results] 30 weeks on 1.7mg, full numbers, ask me anything boring in c/maintenancephase · 51 points · 2 years ago
maintenance is a phase, not a finish line
comment on someone explain NHS to me like I have not read a paper in years in c/glp1uk · 100 points · 2 years ago
an online consultation that asks you nothing is not a consultation
comment on week 17 check-in — 4kg down, fatigue manageable, one thing confusing me in c/cagrilintide · 138 points · 2 years ago
nothing here is approved as a standalone product and research material is not for human use
comment on Germany: pricing, and what it actually costs here in c/glp1uk · 70 points · 2 years ago
tier 3 waiting lists are measured in years, not months
comment on unpopular opinion: most of what gets said here about hazard ratio is guesswork in c/trialwatch · 1 points · 2 years ago
read the endpoint before you read the headline
comment on how much of what we believe about endpoint actually comes from SURMOUNT threads in c/trialwatch · 13 points · 2 years ago
Not convinced. Cross-trial comparison between two programmes with different populations and designs is not a comparison.
comment on [Meta] the lyophilised rule is doing its job and people should stop complaining in c/coldchain · 1 points · 2 years ago
powder at room temperature for a few days is usually a non-event