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c/tirzepatide·submitted 1 year ago by u/nz_unfunded

someone explain dual agonist to me like I have not read a paper in years

Discussionbranch of 7 comments

Genuine question, and the title is the question: someone explain dual agonist to me like I have not read a paper in years. Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved. Held 7.5 for five months. Everyone kept asking when I was going…

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7 comments, started 1 year ago
u/discount_math_dm235 points·1 year ago

The thing nobody warned me about was how much of this is logistics — storing it, remembering it, the same day every week.

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u/rania_diallo127 points·1 year ago

Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.

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u/ahmed_fonseca60 points·1 year ago

Push back: "gentler than sema" is a population statement.

Saving this one. It is the clearest statement of the stall problem I have read here.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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