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c/t2dglp1·submitted 6 months ago by u/joaquin_trevino

hypoglycaemia: the version I wish someone had shown me in week 1

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Reporting in. hypoglycaemia: the version I wish someone had shown me in week 1. The diabetes and obesity programmes are separate, with different populations and different primary endpoints. Reading a result across from one to the other is not a comparison. Incretin-based agents stimulate insulin secretion in a…

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8 comments, started 6 months ago
u/sanne_laurent151 points·6 months ago·edited

A1c reflects average glycaemia over roughly the preceding three months, weighted towards the most recent weeks. It cannot show variability and it lags any change you make.

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u/appeal_letter_al124 points·6 months ago

A1c, CGM, or fingersticks — which are we discussing?

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Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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