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c/sideeffects·posted 1 year ago by u/britt_abubakar

[Discussion] nausea is doing more work than we give it credit for

Discussion Long Haul ×5

nausea is doing more work than we give it credit for. Change my mind, genuinely — I have no stake in being right about this.

Keeping a log, and what to put in it.

One line a day: dose, day since injection, what the symptom was and how bad out of five, and roughly what you ate. Two months of that fits on one page and the pattern is obvious on paper in a way it never is in your head.

Mine showed a clean day-two-to-day-four window I had been describing as "random". Once you can see the pattern you can plan around it, and planning around it is most of the relief.

Kept a one-line-a-day log for two months. The pattern was obvious on paper and invisible in my head.

The pattern almost everyone here describes, written out once so it can be linked.

A step up is followed by a rough window — commonly early fullness arriving the day after the shot and easing by day four, worst in the first fortnight, then flattening out. At a stable dose it usually settles further. Constipation and fatigue tend to track intake and fluid rather than the compound directly, which is why the unglamorous answers work.

What sits outside that pattern: severe pain, symptoms that appear from nowhere weeks into a stable dose, or anything getting worse rather than better over a month. None of that is a board question and none of us can answer it for you.

Happy to answer the boring questions. Those are usually the ones worth asking.

573 up / 16 down97% upvoted21 commentsid bjnurs17 Oct 2024

21 comments

21 in this archive, depth 5

best — the order this archive was captured in

u/ferran_krastev70 points·1 year ago

A symptom that begins the day after the shot and fades by day four tracks the exposure curve. One that appears at random in week 72 probably does not, and that is worth saying to a clinician rather than to us.

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u/laila_delgado21 points·1 year ago

What is intake actually looking like — fibre and water especially?

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[removed]13 points·1 year ago

[removed by moderator]

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u/coring_the_stopper8 points·1 year ago

Right, and the hair thing is worth repeating: it tracks the rate of loss rather than the compound, and it stops.

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u/zeynep_ndiaye56 points·1 year ago

Hair shedding after significant weight loss is a telogen effect that follows the rate of loss. It is not specific to these compounds and it resolves.

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u/rafael_ostergaard42 points·1 year ago

Severe or persistent abdominal pain sits outside the pattern this board can usefully discuss. The honest answer there is that it needs someone who can examine you.

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u/britt_abubakarOP-32 points·1 year ago

Severe, or unpleasant? They are genuinely different questions and the answers diverge.

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u/rania_marchand1 point·1 year ago

Nobody warned me about constipation and I would have liked the warning. It was not dangerous, it was just deeply unpleasant and completely unexpected.

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u/constipation_clubMOD17 points·1 year ago

Flair set to Question. Also the standing reminder that nothing on this board is medical advice.

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u/fatima_asante5 points·1 year ago

the food noise going quiet is the effect people came for, and constipation is the toll for the first fortnight

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u/blank_injection10 points·1 year ago

Which day of the week relative to the shot does it hit?

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u/tl_dr_tina5 points·1 year ago

Which day of the week relative to the shot does it hit?

blank_injection is right about the timing. The day-of-week pattern is the diagnostic bit, not the severity.

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u/britt_abubakarOP6 points·1 year ago

The fatigue turned out to be that I was eating about a third of what I thought I was. Tracked it for a week and the mystery evaporated.

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u/isabela_nilsen22 points·1 year ago

How long after a step up did this start?

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u/blunt_coldbox_20247 points·1 year ago

smaller meals, earlier, is the boring advice that works

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u/thermal_mass_tom10 points·1 year ago

hair shedding follows the weight loss, not the drug, and it stops

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u/tl_dr_tina0 points·1 year ago

Correction: that is a known effect of reduced intake rather than a direct drug effect. The distinction matters because the fix is different.

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u/ayesha_erdogan11 points·1 year ago·edited

How long after a step up did this start?

Adding to this — holding the dose rather than stepping is the option people forget they have.

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u/fatima_asante3 points·1 year ago

Reflux was the one that got me. Stopped eating in the three hours before bed and it went from nightly to almost never.

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u/amara_haddad2 points·1 year ago

Nothing in this thread is medical advice, including this comment. I am describing a mechanism, not telling anybody what to do about their own week.

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u/blank_injection0 points·1 year ago

Yes. Holding the dose is a real option and it does not mean you have failed at anything.

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