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c/retatrutide·submitted 2 months ago by u/rohan_cardoso

does phase 2 actually matter or is it forum lore at this point

Trial Databranch of 6 comments

does phase 2 actually matter or is it forum lore at this point, and I want the answer with the reasoning attached rather than just the conclusion. Where the evidence actually stands, since every thread here assumes a different answer. Phase 2 reported a large mean body weight change at 48 weeks across a few hundred…

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6 comments, started 2 months ago
u/trialwatch_theotrial nerd186 points·2 months ago

the TRIUMPH programme is still running, so anything definitive is premature

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u/bilal_osei130 points·2 months ago

the TRIUMPH programme is still running, so anything definitive is premature

trialwatch_theo is right about the escalation being the variable. It explains most of the difficult reports here.

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[deleted]48 points·2 months ago

[deleted]

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u/noor_ivaturi62 points·2 months ago

Independent purity testing on this compound is thin compared with the older molecules, simply because fewer members have paid for it. Fewer results means wider uncertainty, not a verdict.

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u/deleted_my_history51 points·2 months ago

That is body weight change, not fat mass. The trials report the first and people quote it as the second.

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u/reta_and_regret26 points·2 months ago

wait for phase 3 before you argue about rankings

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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