[Results] 4 weeks on 15mg, full numbers, ask me anything boring
Here it is: 4 weeks on 15mg, full numbers, ask me anything boring. One person, one log, no control group, so read it accordingly. 4 weeks and 15mg — those are the numbers, and they are the ones I am willing to defend. What the glucagon arm is doing, as best anyone can say from public data. GLP-1 and GIP agonism cover…
It is a triple agonist at the GLP-1, GIP and glucagon receptors. The glucagon arm is the genuinely novel component and it is the one with the least human outcome data behind it.
the glucagon component is why the metabolic story reads differently
Small fix — three receptors, not two. GLP-1, GIP and glucagon, and the third one is the reason this compound gets its own board.
That reads as a titration plan for an unapproved compound. This board cannot host that and it should not want to.
Agreed on the heart-rate reports. They are consistent enough across the threads to be worth noting, not enough to be a finding.
The early fullness profile felt different rather than worse. Hard to describe and impossible to quantify, so take it as an impression.
Disagree. "More receptors means more effect" is not how any of this works and the trial data does not support the linear story.
Yes — the comparison threads are apples to oranges and they generate more heat than anything else here.
Right, and it bears repeating that nothing here is approved anywhere and research material is not for human use.
How fast was the escalation? That is usually the variable that explains the reports.
phase 2 data only, and people quote it like it is a label