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c/retatrutide·submitted 2 years ago by u/ferran_krastev

retatrutide — my 21-week log, condensed into one table

Cautionbranch of 6 comments

retatrutide — my 21-week log, condensed into one table. I have gone back and forth on this for months. Where the evidence actually stands, since every thread here assumes a different answer. Phase 2 reported a large mean body weight change at 48 weeks across a few hundred participants with a slow, protocol-driven…

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6 comments, started 2 years ago
u/source_or_silence10 points·2 years ago

Stopped at a low step because there was no reason to go further and no data to tell me what further would do.

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u/ledger_modMOD6 points·2 years ago

Standing reminder in every thread here: unapproved compound, research material is not for human use, nothing on this board is medical advice.

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u/source_or_silence4 points·2 years ago

research-use-only material is not approved for human use, full stop

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u/nikhil_lindqvist2 points·2 years ago

Yes — the comparison threads are apples to oranges and they generate more heat than anything else here.

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u/hassan_nilsen4 points·2 years ago

Correcting my own comment above: that figure was the 36-week interim, not the 48-week endpoint.

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u/arne_amankwah1 point·2 years ago

dose escalation in the trials was slow for a reason

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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