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c/retatrutide·submitted 9 months ago by u/yara_lindholm

[Question] TRIUMPH — what am I missing here

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TRIUMPH — what am I missing here. If this has been answered properly somewhere, link me and I will delete. Read the phase 2 paper twice before ordering anything. Recommend that to anyone in this board: the error bars are the interesting part. The fatigue profile felt different rather than worse. Hard to describe and…

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6 comments, started 9 months ago
u/sena_teixeira313 points·9 months ago

the glucagon component is why the metabolic story reads differently

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u/hugo_pires-21 points·9 months ago·edited

phase 2 data only, and people quote it like it is a label

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u/emil_agyeman0 points·9 months ago

phase 2 data only, and people quote it like it is a label

hugo_pires is right about the escalation being the variable. It explains most of the difficult reports here.

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u/yara_lindholmOP242 points·9 months ago

the glucagon component is why the metabolic story reads differently

Adding the standing caveat: none of this is approved anywhere and research material is not for human use.

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u/liver_enzyme_liz162 points·9 months ago

Small fix — three receptors, not two. GLP-1, GIP and glucagon, and the third one is the reason this compound gets its own board.

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u/ewan_zielinski202 points·9 months ago

Kept a log specifically because there is so little published. It is one person and it is not data.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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