GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Archived. This submission is more than a year old. Votes and new comments are closed, and some of the advice in it may have been superseded — check the community wiki for the current version.
6k
c/retatrutide·posted 1 year ago by u/trialwatch_theo

genuine question about dose escalation that I am slightly embarrassed to ask

Discussion Long Haul ×7 Slow Clap ×3 Cold Box ×3

Slightly embarrassed to be asking this, but: genuine question about dose escalation that I am slightly embarrassed to ask.

The early fullness profile felt different rather than worse. Hard to describe and impossible to quantify, so take it as an impression.

Watched heart rate on a wearable across twelve weeks because the threads said to. It moved a little and I have no idea whether that means anything.

The thing that surprised me was how much of the discussion here is inference rather than measurement.

Please do not ask me what dose you should be on. I genuinely do not know and neither does anyone else here.

6,738 up / 697 down91% upvoted49 commentsid 1v5x482 Dec 2024

49 comments

11 in this archive, depth 4

best — the order this archive was captured in

u/freya_baptista556 points·1 year ago

It is a triple agonist at the GLP-1, GIP and glucagon receptors. The glucagon arm is the genuinely novel component and it is the one with the least human outcome data behind it.

replysharereportpermalink
u/cagrilintide_enthusiast186 points·1 year ago

Kept a log specifically because there is so little published. It is one person and it is not data.

replysharereportpermalink
u/iman_castellanos394 points·1 year ago

not approved anywhere, which is the single most important fact in this board

replysharereportpermalink
u/tired_ledger_notes101 points·1 year ago

heart rate is the thing people report watching

replysharereportpermalink
u/nikhil_asante84 points·1 year ago

wait for phase 3 before you argue about rankings

replysharereportpermalink
u/rosa_almeida248 points·1 year ago

not approved anywhere, which is the single most important fact in this board

This is the sentence the rest of the board should read first. Phase 2 is not a label.

replysharereportpermalink
u/jarno_cabrera317 points·1 year ago

Nothing containing this compound is approved anywhere. Research-use-only material is not approved for human use, and that is a statement of fact rather than a disclaimer.

replysharereportpermalink
u/incretin_ivypharmacology266 points·1 year ago

How fast was the escalation? That is usually the variable that explains the reports.

replysharereportpermalink
load more comments (3) →
About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

65kmembers
130submissions
Sep 2023created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.