week 19 check-in — 9kg down, early fullness manageable, one thing confusing me
week 19 check-in — 9kg down, early fullness manageable, one thing confusing me, logged the same way every week so the comparison is at least internally fair. The numbers the title promised, since a headline without them is worthless: week 19 and 9kg. Everything below is context for those. Kept a log specifically…
Increases in heart rate have been reported across this receptor class. The magnitude and clinical significance are exactly what phase 3 is powered to establish.
Yes — the glucagon arm is what makes it a different proposition rather than a stronger version of the others.
This. The phase 2 result was genuinely large and it was also 48 weeks in a few hundred people.
dose escalation in the trials was slow for a reason
That is body weight change, not fat mass. The trials report the first and people quote it as the second.
Are you comparing against phase 3 numbers for something else? They are not comparable.
Stopped at a low step because there was no reason to go further and no data to tell me what further would do.