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c/researchpeptides·submitted 1 year ago by u/escrow_evangelist

[Lab] 10th independent test on GL Biochem — 99.4% on a claimed 99.0%, and the trend is the interesting part

Labbranch of 16 comments

Posting this because the title is the whole finding — 10th independent test on GL Biochem — 99.4% on a claimed 99.0%, and the trend is the interesting part — and a number without its method is a rumour. The relevant figures are 99.4% and 99.0%, and they come from the same log I have kept the whole time.…

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This branch

16 comments, started 1 year ago
u/line_bergstrom152 points·1 year ago

Net peptide content accounts for counterion, water and residual solvent. On some of these compounds the gap between purity and net content is substantial and entirely honest.

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u/refund_ledger73 points·1 year ago

Push back: handling advice from one compound does not transfer to another just because both are peptides.

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u/sigrid_kaufmann16 points·1 year ago

Bought small on anything without a testing history here. That rule has never once cost me anything.

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u/nayeli_iyer19 points·1 year ago

For any compound with a thin testing history, identity is the first question. Mass spectrometry against a theoretical mass answers it; an area-percent purity figure does not.

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u/insulin_syringe_ian10 points·1 year ago

Correction: that name covers two different molecules and the thread has been discussing both as one.

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u/search_before_post3 points·1 year ago

lyophilised and stored cold is the default for a reason

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u/prior_auth_painappeals2 points·1 year ago

a mass spectrum costs little and answers the real question

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u/old_account_202375 points·1 year ago

I would not treat catalogue breadth as a quality signal. It is a business decision, not an analytical one.

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u/enzo_danquah51 points·1 year ago

That result is an area percent from an unspecified method, which is not the same as the identity confirmation being discussed.

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u/analog_alphabet40 points·1 year ago

Disagree — that name refers to at least two different molecules depending on who is selling it. The thread needs to be specific.

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u/rekha_mbeki83 points·1 year ago·edited

What storage conditions did they specify?

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u/naomi_antonsen52 points·1 year ago

Which exact molecule? That name covers more than one.

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u/yusuf_achebe79 points·1 year ago·edited

Net peptide content on the certificate?

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u/employer_carveout0 points·1 year ago

Yes. Naming conventions in this corner are loose enough that the same word covers several different molecules.

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u/isabela_nilsen18 points·1 year ago·edited

Asked CPC which lines they keep in regional stock versus make to order and got a clear split. It changed what I ordered.

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