maintenance is the most under-discussed thing on this board
maintenance is the most under-discussed thing on this board. I have gone back and forth on this for months. Chased the last three kilos with a dose increase and got a fortnight of nausea and no change in the number. Been at maintenance for 23 months on 0.5mg. Nothing happens. That is the whole report and it took me a…
Interval stretching changes the exposure profile: with a week-long half-life, moving to ten or twelve days lowers trough concentration more than it lowers average exposure. That is why appetite return is often the first thing noticed.
What is the plan if the drift continues for another month?
Withdrawal studies in this class consistently show substantial regain after discontinuation. That is a pharmacological finding about a chronic condition, not a statement about anyone’s discipline.
I would not treat a two-kilo range as drift requiring action. That is ordinary weight variation.
Two years at maintenance. The logistics are the only remaining work — ordering, storing, remembering.
the trials that looked at withdrawal are unambiguous about what follows