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am I the only one who found maintenance harder than the injections

Regain Long Haul ×1 Sourced ×3

Genuine question, and the title is the question: am I the only one who found maintenance harder than the injections.

Dose reduction and interval extension are different interventions. Halving the dose keeps the rhythm and lowers the level; stretching keeps the level and lowers the frequency, with a lower trough.

Interval stretching changes the exposure profile: with a week-long half-life, moving to ten or twelve days lowers trough concentration more than it lowers average exposure. That is why appetite return is often the first thing noticed.

Withdrawal studies in this class consistently show substantial regain after discontinuation. That is a pharmacological finding about a chronic condition, not a statement about anyone’s discipline.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

1,958 up / 542 down78% upvoted47 commentsid 1q7ecc19 Aug 2024

47 comments

29 in this archive, depth 4

best — the order this archive was captured in

u/britt_abubakar92 points·1 year ago

None of this is a taper plan. What dose holds for you is a question for somebody with your history in front of them.

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u/hedda_ekstrom56 points·1 year ago

Stretching the interval, reducing the dose, or both?

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u/cold_chromatogram_only-27 points·1 year ago

monthly weigh-ins are enough at this stage

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u/karim_hartmann1 point·1 year ago

Correction: that trial measured regain after withdrawal, not failure of the drug during treatment. Very different claim.

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u/hub_opssite staff1 point·1 year ago

do not chase the last two kilos with a dose increase

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u/nikhil_lindqvist1 point·1 year ago

Been at maintenance for 2 months on 15mg. Nothing happens. That is the whole report and it took me a while to accept it as success.

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u/fabio_kuipers1 point·1 year ago

regain after stopping is the expected outcome, not a personal failure

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[removed]1 point·1 year ago

[removed by moderator]

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u/fatima_asante41 points·1 year ago

Yes — interval stretching and dose reduction are different levers and people use the words interchangeably.

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u/fatima_yildiz56 points·1 year ago

Maintenance is the phase with the least published guidance and the most individual variation, which is precisely why board consensus here is worth less than usual.

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u/still_here_2026MOD18 points·1 year ago

Left up. It is a maintenance report with a duration attached and those are rarer than they should be.

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u/santiago_lindqvist41 points·1 year ago

Appetite returning before the scale moves follows from the mechanism: the appetite effect is the proximal one and weight is the lagging integrated outcome.

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u/anya_rautio25 points·1 year ago

Weigh monthly now. Best change I made in the whole run and it cost nothing.

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u/taper_off_tabitha14 points·1 year ago

That reads like a taper schedule and this board cannot hand those out.

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u/mod_cold_roommod · c/coldchain30 points·1 year ago

Body weight varies by a couple of kilos over days in stable people through fluid, glycogen and gut content. A range is not a trend.

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u/laila_almeida16 points·1 year ago

I would not treat a two-kilo range as drift requiring action. That is ordinary weight variation.

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u/erez_baptista5 points·1 year ago

maintenance is a phase, not a finish line

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u/rohan_cardoso9 points·1 year ago

Cosigning on planning it in advance. Deciding what maintenance looks like while still losing is much easier than deciding it in a panic.

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u/rohan_cardosoOP4 points·1 year ago

Did you decide what maintenance would look like before you got here?

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u/draw_up_dizzy19 points·1 year ago·edited

Body weight varies by a couple of kilos over days in stable people through fluid, glycogen and gut content.

Adding one thing — decide what maintenance looks like before you arrive at it.

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u/anya_rautio5 points·1 year ago

find the dose that holds, then stop optimising

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u/constipation_clubside effects4 points·1 year ago

Chased the last three kilos with a dose increase and got a fortnight of muscle cramps and no change in the number.

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u/rohan_cardosoOP24 points·1 year ago

The habits from the losing phase are what carry it now. That is not inspirational, it is just what happened.

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u/rohan_cardosoOP17 points·1 year ago

seven days to ten to twelve is the sequence people here describe

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u/fatima_yildiz8 points·1 year ago·edited

seven days to ten to twelve is the sequence people here describe

Disagreeing with this bit: a two-kilo range is not drift and treating it as a problem creates one.

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u/arne_ndiaye16 points·1 year ago

Push back: that is not a plateau, that is maintenance. You have arrived and you are describing it as a failure.

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u/still_here_202618 points·1 year ago

Not convinced. Interval stretching changes your exposure profile, not just the total, and the two are not equivalent.

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u/viktor_erdogan15 points·1 year ago

the goal weight you picked at week 1 was a guess

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u/transit_variance9 points·1 year ago·edited

Is the goal weight still the one you picked at the start?

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The part nobody posts about: what happens at goal weight. Finding a lowest effective dose, dose-interval stretching, regain risk data, muscle retention, the psychology of not having a number to chase, and staying on indefinitely versus tapering.

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