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c/glp1muscle·posted 6 months ago by u/tuva_kirchner

help me understand lean mass, I have read the wiki twice

Results Clean Column ×3 Slow Clap ×2

help me understand lean mass, I have read the wiki twice. I would rather ask a basic question now than get this wrong quietly for two months.

Two scans on the same machine 24 months apart. Lean mass held better than I expected and the lifts told the same story for free.

Kept the same programme for a year instead of changing it every six weeks. That was the change that worked.

Compared two scans from different clinics and panicked over a difference that was inside the error margin.

Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.

1,993 up / 318 down86% upvoted49 commentsid 36uau228 Jan 2026

49 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/noor_ivaturi176 points·6 months ago

Some lean mass loss accompanies weight loss in any deficit. Resistance training and adequate protein intake are the two interventions with the best evidence for limiting the proportion.

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u/karl_fischer_kev47 points·6 months ago

Started weighing protein rather than estimating it. The gap between what I thought and what I ate was embarrassing.

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u/tuva_kirchnerOP29 points·6 months ago·edited

Have the lifts held, dropped, or moved around?

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u/tuva_kirchnerOP114 points·6 months ago

DEXA has a real error margin and people quote it to one decimal

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u/mariam_cabrera254 points·6 months ago

Strength retention is an imperfect but free longitudinal proxy: it is affected by neural factors and by being in a deficit, so it tracks tissue change loosely rather than exactly.

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u/first_pen_fear88 points·6 months ago

grip strength and lift numbers are cheap longitudinal markers

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u/tuva_kirchnerOP54 points·6 months ago·edited

Are you comparing against your own baseline or against a published average?

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u/sarcopenia_watchMOD84 points·6 months ago

Removed a prescriptive nutrition target aimed at another member. Describe your own intake instead.

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u/constipation_clubside effects27 points·6 months ago

Removed a prescriptive nutrition target aimed at another member.

sarcopenia_watch is right that protein becomes a logistics problem when appetite drops.

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u/bilal_adebayo13 points·6 months ago·edited

Correction: those scans are from different machines, and the difference you are describing is within the measurement error.

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u/milos_vestergaard11 points·6 months ago

Right — strength retention is a free proxy and it tracks better than most people expect.

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u/andres_restrepo5 points·6 months ago

Small fix — that is fat-free mass, not muscle mass. The scan cannot separate them the way the post assumes.

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u/first_pen_fear-33 points·6 months ago

the same DEXA machine or it is not a comparison

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u/hassan_chowdhury1 point·6 months ago

losing weight slower does not automatically preserve more lean mass

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u/dario_boateng1 point·6 months ago

Same. Volume over novelty. Changing programme every six weeks cost me a year.

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[deleted]1 point·6 months ago

[deleted]

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u/andres_restrepo1 point·6 months ago

Agreed — protein and resistance training. Everything else in these threads is a rounding error on those two.

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u/tidy_vialdrawer_watch1 point·6 months ago

the same DEXA machine or it is not a comparison

Agreed — and same machine, same conditions, or the two scans are not comparable.

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u/cold_chromatogram44 points·6 months ago

the appetite effect makes eating enough protein a logistics problem

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u/matias_falk22 points·6 months ago

Disagree — slower loss does not automatically preserve lean mass. Protein and training do the work, not the rate on its own.

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u/erez_yilmaz8 points·6 months ago

Yes. Lean mass change during weight loss is expected; the useful question is the proportion, not whether it happens.

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u/kian_verhoeven3 points·6 months ago

the scale cannot distinguish tissue types and never could

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u/meera_oyelaran12 points·6 months ago·edited

That protein figure is grams per day, not grams per kilogram. Different claim entirely.

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u/skip_week_sceptic64 points·6 months ago

On comparing yourself to composition figures from trials.

Published composition data comes from supervised populations with structured protocols, standardised scanning, and analysis populations that have been defined in advance. Your two scans at a local clinic, taken in different states of hydration, are not the same measurement.

Use your own baseline. The question worth asking is whether your own trajectory is going the way you want given what you are actually doing, and the honest answer usually requires measuring protein rather than estimating it and being truthful about training frequency. Neither of those is advice — a programme and a target are things to work out with somebody who knows your history.

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u/nayeli_fonseca27 points·6 months ago

I would not change the programme on the strength of one scan. The measurement error is larger than the effect you are reacting to.

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u/alcohol_aversion17 points·6 months ago

How to make a DEXA comparison mean anything.

Same machine, same clinic, same protocol. Same hydration and fasting state, as far as you can manage. At least three to four months apart, because the measurement error is large relative to short-term change. Three scans rather than two, because the first pair cannot distinguish a trend from noise.

Do less than that and you have two numbers with an offset of unknown size, which people then react to by rebuilding a training programme. The free alternative — a few tracked lifts and a monthly waist measurement — is directionally informative, costs nothing, and is far harder to over-interpret.

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u/protein_first_pnutrition6 points·6 months ago

FFMI is a ratio and it moves when either term moves

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u/tomas_kimani14 points·6 months ago

Lost slower for six months deliberately and my composition change was not obviously different. Training was what mattered.

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u/reflux_report10 points·6 months ago

Hydration status and fasting state affect the lean mass estimate. Standardising both is the difference between a comparison and a coin toss.

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u/halima_mbeki5 points·6 months ago

DEXA has a meaningful coefficient of variation, and it differs between machines and protocols. Comparing scans from different clinics adds a systematic offset that is invisible on the report.

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About c/glp1muscle

Lean-mass retention during rapid weight loss: protein targets, resistance-training minimums, DEXA and BIA measurement reality, FFMI tracking, and the sarcopenia question that nobody funded a proper trial for.

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