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c/cagrilintide·submitted 1 year ago by u/yara_mensah

[Results] 2 weeks on 7.5mg, full numbers, ask me anything boring

Labbranch of 6 comments

2 weeks on 7.5mg, full numbers, ask me anything boring. Full detail below, and I have tried to keep the editorialising out of it. Pulling the figures out of the title: 2 weeks and 7.5mg. All of it is written down as it happened rather than reconstructed. The engineering problem was duration: native amylin is…

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6 comments, started 1 year ago
u/zeynep_duarte49 points·1 year ago

Asked a question here that turned out to be based on a mechanism confusion. Three people untangled it patiently.

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u/zaid_grimaldi24 points·1 year ago

Independent purity data on this compound is sparse compared with the older molecules, simply because far fewer members have paid for testing. Sparse data means wide uncertainty, not a verdict.

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u/liv_dumitru12 points·1 year ago

long-acting amylin is the whole point of the molecule

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u/ilias_kaufmann39 points·1 year ago

phase 3 data will change most of what gets said here

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u/hydration_hank32 points·1 year ago

Cosigning on the thin independent data. Fewer members test this, so the bands are wider and should be treated that way.

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[deleted]13 points·1 year ago

[deleted]

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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