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c/bpc157·submitted 2 years ago by u/anya_erdogan

someone explain pentadecapeptide to me like I have not read a paper in years

Questionbranch of 6 comments

Question in the title, detail here: someone explain pentadecapeptide to me like I have not read a paper in years. It is a fifteen-residue peptide with a published sequence, which makes synthesis straightforward and makes identity verification the meaningful test rather than an optional extra. Short peptides in…

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6 comments, started 2 years ago
u/milos_mensa8 points·2 years ago

ask for the mass spectrum, not just the purity number

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u/anya_erdoganOP12 points·2 years ago

read the actual papers, they are more modest than the summaries

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u/search_before_post0 points·2 years ago

read the actual papers, they are more modest than the summaries

This is the point that should be at the top of every thread here. Identity first.

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u/throwaway_91821 point·2 years ago

This is the point that should be at the top of every thread here.

Agreed — and the preclinical to clinical gap is where nearly all the overclaiming happens.

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u/joaquin_ivaturi4 points·2 years ago

Regulatory classification differs between jurisdictions and has changed in several of them recently. Any answer to a status question needs a place and a date attached.

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u/throwaway_91821 point·2 years ago

Yes — the rodent literature is real and it is rodent literature. The gap to a human claim is enormous and it gets crossed in one sentence here.

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About c/bpc157

BPC-157 as it actually is: a pentadecapeptide with a genuinely interesting rodent tendon-and-gut literature, near-zero controlled human data, a naming and sequence mess in the supply chain, and a regulatory status that changed sharply in several countries.

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