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c/bloodwork·submitted 1 months ago by u/elin_varga

tried A1c for 18 weeks. here is what happened.

Discussionbranch of 12 comments

tried A1c for 18 weeks. here is what happened, and I am aware this is a minority view on this board. 18 weeks. Those are measured, not estimated, and not rounded up in my favour. Took a baseline the week before starting purely because this board told me to. Best five minutes I have spent on this. Draw at the same…

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12 comments, started 1 months ago
u/ahmed_fonseca23 points·1 months ago

Time of day, fasting state, hydration and recent exercise all move common markers. Standardising the draw conditions is free and it removes most of the apparent variability.

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u/cormac_roos18 points·1 months ago

Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.

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u/emeka_chowdhury7 points·1 months ago

same lab, same conditions, or you are comparing noise

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u/step_therapy_s5 points·1 months ago

Disagree with reading anything into that. One value, one morning, and you changed two other things in the same window.

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u/cormac_erdogan3 points·1 months ago

This. Reference ranges are population intervals, not targets, and conflating them causes a lot of unnecessary alarm here.

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u/yara_mensah0 points·1 months ago

Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.

Disagreeing with this bit: that change is confounded by the weight loss itself and cannot be attributed.

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u/andres_restrepo1 point·1 months ago·edited

Disagreeing with this bit: that change is confounded by the weight loss itself and cannot be attributed.

yara_mensah is right that a reference interval is not a target. It is a description of a population.

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u/kaia_kuusela14 points·1 months ago

Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong.

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u/isabela_guerrero7 points·1 months ago·edited

Reference intervals are typically the central 95% of a reference population.

This is the sentence to read before anybody panics about a single value.

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u/diego_sorensen4 points·1 months ago

ApoB is the one worth adding if you only add one

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u/skip_week_sceptic3 points·1 months ago

That comparison crosses two labs with different assays. The difference you are describing may be the method.

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u/mikkel_ogunleye10 points·1 months ago

Right, and weight loss itself moves several markers, so attribution is harder than these threads assume.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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