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c/bloodwork·submitted 3 days ago by u/diego_almeida

[Baseline] get these before you start, you cannot go back for them later

Baselinebranch of 9 comments

get these before you start, you cannot go back for them later. Making the case below, and I expect to lose some of it in the comments. Added ApoB to the panel after a thread here. It told me something the standard lipid panel had been hiding. My ApoB moved and I spent a fortnight convinced I knew why. The repeat six…

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9 comments, started 1 days ago
u/flair_enthusiast23 points·1 days ago

Push back: a value just outside a reference interval is a common finding in healthy people. It is a reason to repeat.

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u/copay_card_cc6 points·1 days ago

How to make a panel worth comparing, which is most of the value people leave on the table.

Standardise the conditions: same lab, same fasting state, same rough time of day, same point in the week, similar hydration. Take a baseline before you change anything. Repeat any surprising value before acting on it. Change one thing at a time if you want to attribute anything to it.

Do that and a year of panels is a trend. Skip it and a year of panels is a collection of unrelated mornings, which is what most of the alarmed posts here are actually describing.

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u/anya_rautio5 points·1 days ago

lab reference ranges are not treatment targets

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u/diego_almeidaOP3 points·1 days ago

Correcting my own comment: the two draws were 19 weeks apart, not the figure I gave earlier.

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u/santiago_rasmussen31 points·1 days ago

Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong.

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u/osman_eriksen45 points·1 days ago

Compared two draws across two labs and spent a week worrying before finding out the assays were different.

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u/jonas_cardoso15 points·1 days ago

weight loss itself moves several of these independently

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u/skip_week_sceptic7 points·1 days ago

weight loss itself moves several of these independently

This is the sentence to read before anybody panics about a single value.

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[deleted]3 points·1 days ago

[deleted]

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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