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c/bloodwork·submitted 1 year ago by u/bac_water_bandit

ferritin — 15 things I got wrong before I got it right

Resultsbranch of 11 comments

ferritin — 15 things I got wrong before I got it right. It is the sort of thing everyone half-believes and nobody writes down. ApoB counts atherogenic particles rather than the cholesterol they carry, which is why it can diverge from LDL-C and why it is the addition most worth making. Time of day, fasting state,…

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11 comments, started 1 year ago
u/isabela_guerrero72 points·1 year ago·edited

That comparison crosses two labs with different assays. The difference you are describing may be the method.

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u/laila_yilmaz38 points·1 year ago

Agreed on assay changes. A lab switching platforms between your draws is invisible unless you ask.

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u/whois_wanda10 points·1 year ago

Same view — ApoB if you add one thing. It answers a question the standard panel only gestures at.

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u/lina_almeida26 points·1 year ago

Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.

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u/a1c_arcT2D9 points·1 year ago

Careful — that is a question for whoever ordered the panel, and nobody in this thread can answer it responsibly.

Disagreeing with this bit: that change is confounded by the weight loss itself and cannot be attributed.

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u/bac_water_banditOPreconstitution4 points·1 year ago

Correcting my own comment: the two draws were 8 weeks apart, not the figure I gave earlier.

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u/ismael_eriksen2 points·1 year ago

Same lab as the previous draw?

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u/baseline_drifteranalytical-29 points·1 year ago

Compared two draws across two labs and spent a week worrying before finding out the assays were different.

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u/kofi_balogun15 points·1 year ago

Fasting or not, and what time of day?

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u/step_therapy_s9 points·1 year ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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u/tomas_kimani7 points·1 year ago

Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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