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u/bac_water_bandit

Bacteriostatic water, 0.9% benzyl alcohol, 28 days, room temp after first puncture. Write it down.

long-standing contributor · reconstitution · joined 2 Dec 2023

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comment on reconstituted vial left out for five hours — bin it or not in c/coldchain · 104 points · 1 days ago

you avoided it because the person who sold it to you sent the right one. that is the whole mechanism and it is not reassuring.

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comment on ApoB over LDL-C and i will keep saying it in c/bloodwork · 2 points · 2 days ago

Fasting or not, and what time of day?

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comment on [Results] ALT 34 → 19 in seven months, nothing else changed in c/bloodwork · 1 points · 2 days ago

baseline before you start is worth more than any later panel

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comment on ApoB over LDL-C and i will keep saying it in c/bloodwork · 37 points · 3 days ago

Tracked eGFR against the weight trend for a year. The correlation was much weaker than I expected and that was worth knowing.

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comment on [Correction] the concentration table going round is off by a factor of ten in c/reconstitution · 60 points · 6 days ago

Left up and flaired Explainer — the numbers in this one check out.

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comment on [Math] someone check my arithmetic before i draw this up in c/reconstitution · 59 points · 9 days ago

The whole calculation, once, with real numbers.

You have a 10mg vial. You add 1mL of bacteriostatic water. Concentration is mass over volume: 10mg/mL. A U-100 insulin syringe is graduated at 100 units per millilitre, so one unit is 0.01mL.

To draw 2mg you need 2 divided by 10 millilitres, which is 20 units on the barrel. Write "10mg/mL" on the vial in marker before you put it away, and you never have to do this again for that vial.

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comment on [Explainer] units are volume, mg are mass, this is the #1 error on this site in c/reconstitution · 15 points · 12 days ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

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comment on [Explainer] units are volume, mg are mass, this is the #1 error on this site in c/reconstitution · 48 points · 13 days ago

The arithmetic in full: concentration is mass over volume, so 5mg into 2mL gives 2.5mg/mL. A U-100 syringe is graduated at 100 units per millilitre, so 1mg is 1 divided by 2.5 millilitres, which is 40 units.

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comment on cloudy after reconstitution — discard, right? right. in c/reconstitution · 47 points · 13 days ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

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comment on reconstituted at 1mL instead of 2mL and caught it before injecting. lucky. in c/reconstitution · 24 points · 17 days ago

Reminder: this board does maths, not dosing. Nobody here tells another member what amount to take.

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comment on help me understand mg/mL, I have read the wiki twice in c/reconstitution · 46 points · 1 months ago

units are a volume on a U-100 syringe, not a dose

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comment on the bacteriostatic water thing finally clicked for me and I want to write it down in c/reconstitution · 17 points · 1 months ago

Bacteriostatic or plain sterile water?

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comment on someone explain concentration to me like I have not read a paper in years in c/reconstitution · 355 points · 1 months ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

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comment on the bloodwork thing finally clicked for me and I want to write it down in c/bloodwork · 1 points · 2 months ago

Yes — same lab, same fasting state, same rough time of day, or the comparison is doing nothing.

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comment on the bloodwork thing finally clicked for me and I want to write it down in c/bloodwork · 4 points · 2 months ago

the trend line matters more than any single value

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comment on does mg/mL actually matter or is it forum lore at this point in c/reconstitution · 61 points · 2 months ago

the powder cake sits at the bottom, the volume you add is the volume that counts

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comment on does mg/mL actually matter or is it forum lore at this point in c/reconstitution · 201 points · 2 months ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

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comment on does bacteriostatic water actually matter or is it forum lore at this point in c/reconstitution · 1 points · 2 months ago

more water is not more drug, it is the same drug in a bigger volume

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comment on genuine question about concentration that I am slightly embarrassed to ask in c/reconstitution · 52 points · 3 months ago

I would not round that figure. At 2.5mg/mL a rounding error of two units is a real fraction of the intended amount.

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comment on genuine question about concentration that I am slightly embarrassed to ask in c/reconstitution · 156 points · 3 months ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

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comment on unpopular opinion: most of what gets said here about bacteriostatic water is guesswork in c/reconstitution · 1 points · 3 months ago

more water is not more drug, it is the same drug in a bigger volume

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comment on three years of dead space threads, summarised so you do not have to read them in c/reconstitution · 36 points · 4 months ago

Bacteriostatic water contains benzyl alcohol as a preservative, which is what makes repeated entry into the same vial reasonable. Plain sterile water has no preservative.

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comment on help me understand concentration, I have read the wiki twice in c/reconstitution · 39 points · 5 months ago

Same.

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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comment on why does nobody talk about concentration in c/reconstitution · 23 points · 5 months ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

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comment on [Discussion] bacteriostatic water is doing more work than we give it credit for in c/reconstitution · 5 points · 6 months ago

the number you write down is the number you will trust at 6am

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comment on the dead space thing finally clicked for me and I want to write it down in c/reconstitution · 54 points · 7 months ago

Left up and flaired Explainer — the numbers in this one check out.

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comment on what would you tell week-1 you about lipids in c/bloodwork · 0 points · 8 months ago

Retitled — the original asserted a causal claim the post does not support.

Agreed — and standardising the draw conditions is the cheapest improvement available.

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comment on reading bacteriostatic water threads from 2024 and half of it aged badly in c/reconstitution · 0 points · 9 months ago

Started reconstituting everything to a round concentration and the six-in-the-morning error rate went to zero.

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comment on [Meta] proposal — a flair for reconstitution posts in c/reconstitution · 8 points · 9 months ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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comment on unpopular opinion: most of what gets said here about dead space is guesswork in c/reconstitution · 26 points · 11 months ago

The whole calculation, once, with real numbers.

You have a 10mg vial. You add 2mL of bacteriostatic water. Concentration is mass over volume: 5mg/mL. A U-100 insulin syringe is graduated at 100 units per millilitre, so one unit is 0.01mL.

To draw 0.5mg you need 0.5 divided by 5 millilitres, which is 10 units on the barrel. Write "5mg/mL" on the vial in marker before you put it away, and you never have to do this again for that vial.

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comment on the baseline labs thing finally clicked for me and I want to write it down in c/bloodwork · 1 points · 1 year ago

Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine.

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comment on A1c — 9 things I got wrong before I got it right in c/bloodwork · 20 points · 1 year ago

Brought the whole set to my clinician rather than one flagged value. Completely different conversation.

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comment on ferritin — my 22-week log, condensed into one table in c/bloodwork · 1 points · 1 year ago

Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine.

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comment on unpopular opinion: most of what gets said here about units are guesswork in c/reconstitution · 470 points · 1 year ago

Left up and flaired Explainer — the numbers in this one check out.

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comment on does reconstitution actually matter or is it forum lore at this point in c/reconstitution · 73 points · 1 year ago

Reminder: this board does maths, not dosing. Nobody here tells another member what amount to take.

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comment on units are the most under-discussed thing on this board in c/reconstitution · 1k points · 1 year ago

Left up and flaired Explainer — the numbers in this one check out.

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comment on someone explain mg/mL to me like I have not read a paper in years in c/reconstitution · 116 points · 1 year ago

Corrected the concentration in the title, which contradicted the body. Nothing else touched.

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comment on ferritin — 15 things I got wrong before I got it right in c/bloodwork · 4 points · 1 year ago

Correcting my own comment: the two draws were 8 weeks apart, not the figure I gave earlier.

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