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c/bloodwork·submitted 1 year ago by u/burned_once_twice

A1c — 9 things I got wrong before I got it right

Questionbranch of 10 comments

A1c — 9 things I got wrong before I got it right — a position I have arrived at slowly and would like tested. Substantial weight loss independently moves lipids, liver enzymes and several other markers. Attributing a change to a compound while losing weight is confounded by design. My ApoB moved and I spent a…

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10 comments, started 1 year ago
u/forest_plot_fionastats50 points·1 year ago

Agreed on assay changes. A lab switching platforms between your draws is invisible unless you ask.

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u/coring_the_stopper39 points·1 year ago

How many weeks between the two measurements?

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u/ismael_eriksen26 points·1 year ago

This. Reference ranges are population intervals, not targets, and conflating them causes a lot of unnecessary alarm here.

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u/coldchain_karencold chain16 points·1 year ago

How many weeks between the two measurements?

Adding the obvious one — take it to whoever ordered the panel. This board cannot read it for you.

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u/burned_once_twiceOP27 points·1 year ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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u/santiago_szabo16 points·1 year ago

the trend line matters more than any single value

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u/yara_mensah13 points·1 year ago

draw at the same point in the week if you want comparability

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u/noor_cardoso8 points·1 year ago

ApoB is the one worth adding if you only add one

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u/bence_zamora8 points·1 year ago

Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.

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u/elin_trevino0 points·1 year ago

Nobody here can interpret your panel and this comment is not doing so.

Agreed — and standardising the draw conditions is the cheapest improvement available.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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