stalled for 15 weeks at 15mg and I refuse to panic this time
stalled for 15 weeks at 15mg and I refuse to panic this time, which sounds obvious until you try to state the evidence for it.
Numbers, in the order they matter: 15 weeks and 15mg.
Compared two draws across two labs and spent a week worrying before finding out the assays were different.
Added ApoB to the panel after a thread here. It told me something the standard lipid panel had been hiding.
If somebody has the same thing measured a different way, post it next to mine and we will see whether they agree.
best — the order this archive was captured in
Substantial weight loss independently moves lipids, liver enzymes and several other markers. Attributing a change to a compound while losing weight is confounded by design.
My TSH moved and I spent a fortnight convinced I knew why. The repeat six weeks later was back in range and I had changed nothing.
Fasting or not, and what time of day?
Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.
ask whether the lab changed its assay between your two draws
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Correcting my own comment: the two draws were 4 weeks apart, not the figure I gave earlier.
That is a non-fasting value and the interval you are comparing it against is a fasting one.
Is that the same assay, or did the lab change platforms?
weight loss itself moves several of these independently
How many weeks between the two measurements?
Took a baseline the week before starting purely because this board told me to. Best five minutes I have spent on this.
Repeat testing before acting is standard practice for a reason: regression to the mean does a lot of work on single outlying values.
I would not draw a line through two points, especially when the second was taken at a different time of day.
Did anything else change in that window — training, intake, hydration?
Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.
Tracked hs-CRP against the weight trend for a year. The correlation was much weaker than I expected and that was worth knowing.
That comparison crosses two labs with different assays. The difference you are describing may be the method.
Yes. Repeat before you react. Almost every alarming single value I have posted here regressed on the repeat.
lab reference ranges are not treatment targets
Same lab as the previous draw?
Brought the whole set to my clinician rather than one flagged value. Completely different conversation.
assay method matters, especially between different labs
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