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c/bloodwork·posted 20 days ago by u/nabila_bakken

lipids got worse on paper while everything else got better. triglycerides explain it.

Baseline Clean Column ×8

lipids got worse on paper while everything else got better. triglycerides explain it. It is the sort of thing everyone half-believes and nobody writes down.

My A1c moved and I spent a fortnight convinced I knew why. The repeat six weeks later was back in range and I had changed nothing.

Compared two draws across two labs and spent a week worrying before finding out the assays were different.

Took a baseline the week before starting purely because this board told me to. Best five minutes I have spent on this.

If somebody has the same thing measured a different way, post it next to mine and we will see whether they agree.

932 up / 133 down88% upvoted54 commentsid 174k2k10 Jul 2026

54 comments

17 in this archive, depth 5

best — the order this archive was captured in

u/leila_vasquez48 points·20 days ago

Different laboratories use different assay platforms with different calibration. Comparing across labs adds a systematic offset that is invisible on the report.

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u/nnt_nate12 points·19 days ago

Different laboratories use different assay platforms with different calibration.

Adding the obvious one — take it to whoever ordered the panel. This board cannot read it for you.

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u/gentle_correctionnice about it23 points·19 days ago

Repeat testing before acting is standard practice for a reason: regression to the mean does a lot of work on single outlying values.

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u/a1c_arcT2D7 points·19 days ago

a single ApoB outside range is a reason to repeat, not to panic

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u/andres_restrepo3 points·19 days ago

Did anything else change in that window — training, intake, hydration?

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u/nabila_bakkenOP-24 points·19 days ago

Repeat testing before acting is standard practice for a reason: regression to the mean does a lot of work on single outlying values.

Agreed — and standardising the draw conditions is the cheapest improvement available.

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u/step_therapy_s1 point·18 days ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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[removed]1 point·18 days ago

[removed by moderator]

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u/heart_rate_bump27 points·19 days ago

baseline before you start is worth more than any later panel

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u/yara_boateng35 points·19 days ago

Added ApoB to the panel after a thread here. It told me something the standard lipid panel had been hiding.

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u/santiago_rasmussen9 points·19 days ago·edited

Tracked ApoB against the weight trend for a year. The correlation was much weaker than I expected and that was worth knowing.

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u/jonas_cardoso38 points·19 days ago

Substantial weight loss independently moves lipids, liver enzymes and several other markers. Attributing a change to a compound while losing weight is confounded by design.

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u/nabila_bakkenOP23 points·19 days ago

That is a non-fasting value and the interval you are comparing it against is a fasting one.

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u/nabila_bakkenOP9 points·19 days ago

How many weeks between the two measurements?

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u/coa_forgery_watch21 points·19 days ago

Cosigning on baseline. The panel I regret most is the one I did not take before starting.

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u/neha_rahimi7 points·19 days ago

ApoB is the one worth adding if you only add one

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u/a1c_arcMOD8 points·19 days ago

Retitled — the original asserted a causal claim the post does not support.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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