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c/bloodwork·submitted 1 year ago by u/yara_antonsen

help me understand ALT, I have read the wiki twice

Questionbranch of 7 comments

Genuine question, and the title is the question: help me understand ALT, I have read the wiki twice. Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine. Tracked triglycerides against the weight trend for a year. The correlation was much weaker than I expected and that was…

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7 comments, started 1 year ago
u/thermal_mass_tom13 points·1 year ago

lab reference ranges are not treatment targets

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u/nabila_bakken3 points·1 year ago

Repeat testing before acting is standard practice for a reason: regression to the mean does a lot of work on single outlying values.

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u/neha_rahimi1 point·1 year ago

Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong.

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u/karl_fischer_kev0 points·1 year ago

Yes. Repeat before you react. Almost every alarming single value I have posted here regressed on the repeat.

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u/customs_seizure_sid2 points·1 year ago

Disagree with reading anything into that. One value, one morning, and you changed two other things in the same window.

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u/vito_chowdhury2 points·1 year ago

I would not draw a line through two points, especially when the second was taken at a different time of day.

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u/whois_wanda1 point·1 year ago

baseline before you start is worth more than any later panel

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What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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