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c/bloodwork·submitted 2 years ago by u/diego_almeida

the baseline labs question that gets asked weekly, answered properly

Baselinebranch of 15 comments

the baseline labs question that gets asked weekly, answered properly. Change my mind, genuinely — I have no stake in being right about this. Repeat testing before acting is standard practice for a reason: regression to the mean does a lot of work on single outlying values. Time of day, fasting state, hydration and…

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15 comments, started 2 years ago
u/karl_fischer_kev302 points·2 years ago

Nobody here can interpret your panel and this comment is not doing so. What a board can usefully do is help you ask better questions of somebody who can.

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u/liver_enzyme_liz101 points·2 years ago

Agreed on assay changes. A lab switching platforms between your draws is invisible unless you ask.

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u/kaia_kuusela54 points·2 years ago

Small fix — a reference interval is not a treatment target, and the post above uses them interchangeably.

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u/employer_carveout353 points·2 years ago

hydration status moves a surprising number of markers

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u/edit_for_clarity263 points·2 years ago·edited

Is that the same assay, or did the lab change platforms?

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u/yara_mensah201 points·2 years ago

Reference intervals are typically the central 95% of a reference population. By construction one person in twenty falls outside one on any given test without anything being wrong.

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[removed]175 points·2 years ago

[removed by moderator]

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u/nabila_bakken81 points·2 years ago

Tracked ApoB against the weight trend for a year. The correlation was much weaker than I expected and that was worth knowing.

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u/greta_chukwu28 points·2 years ago

fasting state and time of day change more than people expect

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u/diego_almeidaOP20 points·2 years ago

Correction: that marker is reported in different units by different labs, which explains the tenfold difference you are seeing.

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u/elise_grimaldi192 points·2 years ago·edited

bring the numbers to someone qualified to read them

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u/karl_fischer_kev103 points·2 years ago

a single ApoB outside range is a reason to repeat, not to panic

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u/noor_cardoso240 points·2 years ago

one measurement is a point, two is a line, three is a trend

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u/britt_marchand63 points·2 years ago

ask whether the lab changed its assay between your two draws

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u/heart_rate_bump16 points·2 years ago

Panicked about a single result, posted here, got told to repeat it, repeated it, and it was fine.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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