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u/medutest_mel

Sends duplicates to two services and compares. Usually they agree. Usually.

member · joined 22 Mar 2024

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Comments — page 3 of 3

comment on how much of what we believe about purity actually comes from below spec threads in c/labresults · 3 points · 1 year ago

I would not post that as a finding. It is a single result and the template asks you to say so.

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comment on [Question] chromatogram — what am I missing here in c/hplc · 0 points · 1 year ago

Carryover from a previous high-concentration injection looks exactly like a small impurity.

nora_lundgren is right — the integration choice is a decision and it should be stated alongside the result.

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comment on [Question] chromatogram — what am I missing here in c/hplc · 1 points · 1 year ago

a blank injection between samples costs four minutes and settles most arguments

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comment on test results — 20 things I got wrong before I got it right in c/labresults · 93 points · 1 year ago

Left up and added to the vendor source page log. Thanks for paying for it and posting it.

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comment on [Meta] the Janoshik rule is doing its job and people should stop complaining in c/labresults · 88 points · 1 year ago

Merged with the other thread on the same batch so the results sit together.

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comment on unpopular opinion: most of what gets said here about integration is guesswork in c/hplc · 58 points · 1 year ago

UV response is not uniform across species. At 214nm you are looking at the peptide bond, which is why it is the working wavelength for this class; at 280nm you only see tryptophan, tyrosine and phenylalanine.

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comment on unpopular opinion: most of what gets said here about integration is guesswork in c/hplc · 128 points · 1 year ago

Not convinced by that integration. Dropping the baseline there absorbs part of the shoulder into the main peak.

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comment on why does nobody talk about purity in c/labresults · 213 points · 1 year ago

date of analysis matters as much as the number

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comment on [Meta] the chromatogram rule is doing its job and people should stop complaining in c/hplc · -10 points · 1 year ago

report the method or do not report the number

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comment on my ferritin moved and I cannot work out whether tracking is why in c/dosinglogs · 14 points · 1 year ago

That is a waist figure in the weight column. Easy mistake and it makes the chart look dramatic.

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comment on genuine question about HPLC that I am slightly embarrassed to ask in c/hplc · 47 points · 1 year ago

reproducibility beats resolution if you only get one of them

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comment on someone explain state board to me like I have not read a paper in years in c/compounding · 579 points · 1 year ago

I would not read the price difference as a quality signal. Most of it is the consultation model, not the vial.

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comment on genuine question about regret that I am slightly embarrassed to ask in c/darkspot · 12 points · 1 year ago

What would you do differently, specifically?

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comment on dose history — my 20-week log, condensed into one table in c/dosinglogs · 15 points · 1 year ago

What is the one column you added late and wish you had from the start?

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comment on Janoshik — 19 things I got wrong before I got it right in c/labresults · 69 points · 1 year ago

Left up and added to the vendor source page log. Thanks for paying for it and posting it.

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comment on do test results actually matter or is it forum lore at this point in c/labresults · 10 points · 1 year ago

GL Biochem came back 99.6% on a claimed 99.0%, which is agreement not a discrepancy

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comment on 5 months in and weight is still the thing I get wrong in c/dosinglogs · 8 points · 1 year ago

Agreed. One line a week that actually gets written beats an elaborate template abandoned in month two.

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comment on [Vendor] FGP vs SWB on the same compound, same month — both cleared 99.0% in c/labresults · 39 points · 2 years ago

Left up and added to the vendor source page log. Thanks for paying for it and posting it.

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comment on reading API source threads from 2024 and half of it aged badly in c/compounding · 65 points · 2 years ago

Is the compound still on the shortage list where you are?

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comment on [Discussion] the purity advice in here is 2 years out of date in c/labresults · 28 points · 2 years ago

Retitled — the original stated a discrepancy the numbers do not show.

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comment on [Discussion] the batch advice in here is 3 years out of date in c/labresults · 45 points · 2 years ago

Same. The WWB results have been sitting in a tight band across lots, which is the useful shape.

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comment on [Lab] 14th independent test on GGPeps — 98.3% on a claimed 97.5%, and the trend is the interesting part in c/labresults · 369 points · 2 years ago

a result with no batch number is about a vial nobody can identify

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comment on [Lab] 14th independent test on GGPeps — 98.3% on a claimed 97.5%, and the trend is the interesting part in c/labresults · 106 points · 2 years ago

Is that the same lot as the one in the thread from last month?

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comment on [Lab] 14th independent test on GGPeps — 98.3% on a claimed 97.5%, and the trend is the interesting part in c/labresults · 122 points · 2 years ago

First result I ever posted here got asked for the batch number and the claim. Fair, and my posts have been better ever since.

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comment on [Lab] 14th independent test on GGPeps — 98.3% on a claimed 97.5%, and the trend is the interesting part in c/labresults · 1.3k points · 2 years ago

Retitled — the original stated a discrepancy the numbers do not show.

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comment on someone explain 503B to me like I have not read a paper in years in c/compounding · 7 points · 2 years ago

Did they name the facility?

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comment on [Lab] 5th independent test on HJ — 99.2% on a claimed 99.0%, and the trend is the interesting part in c/labresults · 76 points · 2 years ago

Merged with the other thread on the same batch so the results sit together.

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comment on how much of what we believe about purity actually comes from batch threads in c/labresults · 366 points · 2 years ago

Area percent and net peptide content are different measurements and most reports give one. Quote which, or the comparison downstream is meaningless.

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comment on [Meta] the method development rule is doing its job and people should stop complaining in c/hplc · 391 points · 2 years ago

axis labels or the trace is decoration

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comment on [Discussion] the 503A advice in here is 2 years out of date in c/compounding · 54 points · 2 years ago

Potency and sterility testing on the finished preparation are separate from any certificate covering the starting material. Ask which you are being shown.

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comment on purity — 19 things I got wrong before I got it right in c/hplc · 152 points · 2 years ago

That is area percent, not mass percent. The trace cannot give you the second one.

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comment on gradient — 17 things I got wrong before I got it right in c/hplc · 11 points · 2 years ago

Agreed, and it is why BCH printing the column and gradient on the certificate is genuinely useful rather than decorative.

hazard_ratio_hal is right — the integration choice is a decision and it should be stated alongside the result.

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