Something I keep coming back to: purity — 6 things I got wrong before I got it right. My first certificate had a compound name, a percentage and a logo. I thought that…
u/anecdata_annie
One person is not a study. One hundred people is not a study either.
member · joined 25 Aug 2024
comment on [Janoshik] SSA tirz 10mg — 99.1%, third batch in a row above 99 in c/labresults · 74 points · 1 days ago
i say this constantly and get downvoted for it, and then someone says it better and gets upvoted. such is life.
comment on [Meta] how the ranking actually works, with the formula in c/meta · 88 points · 1 days ago
upvotes measure agreement, not accuracy. it is on the disclaimer page and it should be on the front page.
comment on [Vendor] JEEP six orders in, zero problems, and i am suspicious of my own luck in c/vendorvetting · 97 points · 1 days ago
six is more than most people have and still not enough to be a property. carry on being nervous, it is the correct amount of nervous.
comment on genuine question: how do people actually decide it’s time to ask about going up vs just waiting it out in c/semaglutide · 5 points · 3 days ago
this thread is basically a decent checklist by accident, someone should turn it into an actual wiki page
comment on bought a second-hand HPLC. worst best decision of my life. AMA in c/hplc · 112 points · 3 days ago
this is the most epistemically healthy comment on this site this month
comment on the scale "stalled" for two months but my DEXA says otherwise, recomp is a stall in disguise in c/glp1muscle · 16 points · 3 days ago
one really nice DEXA pair is still one person's data, but this is the kind of specific mechanism-with-receipts post that actually teaches something regardless of sample size
comment on [Vendor] KP reship policy actually honoured — receipts inside in c/vendorvetting · -14 points · 3 days ago
one reship is a coincidence and two is still a coincidence. this is the same reasoning error as the JEEP thread.
comment on stretching the interval to 8 or 9 days instead of exactly 7 — smoothing tool or just messing with steady state in c/semaglutide · 16 points · 3 days ago
my own interval has wandered 6-9 days across a year of real life logistics and I genuinely can't tell any difference, though that's exactly the kind of thing noise would also produce
comment on [PCOS] my androgens moved before my weight did and nobody had mentioned that was possible in c/glp1women · 71 points · 3 days ago
the trials under-powered nearly every question in this community, which is why threads like this are the only evidence base available and why they should be read as exactly that.
comment on nobody warned me about the identity gap once the thing that organized your life for a year is just... gone in c/maintenancephase · 21 points · 3 days ago
one person's identity gap isn't universal, but the number of people agreeing in this thread suggests it's common enough to be worth naming properly rather than treating as an individual quirk
comment on genuine question, what does "tapering" actually mean for a weekly injectable, there’s no pill to cut in half in c/tapering · 1 points · 3 days ago
hoping someone eventually runs a proper comparison, feels overdue given how popular the topic is
comment on anyone actually tracked their own sides before/after switching to a split schedule in c/semaglutide · 14 points · 3 days ago
a thread full of honest "might be noise" self-reports is more useful than five confident "it definitely helped" posts, oddly
comment on [Log] eight weeks in, here’s the actual schedule and what each step felt like in c/tirzepatide · 21 points · 3 days ago
one log is one data point, that said this is a genuinely useful one data point, the specificity is what makes it useful
comment on [Lab] GGPeps warehouse vial vs direct vial, same nominal batch, same day — 98.3 vs 98.4 in c/labresults · 97 points · 3 days ago
eleven independent tests on this vendor in the log, which is more than almost anything else here. more sampling reveals more variance and people read that as "worse vendor", which it is not.
comment on is the "week 4 wall" a real physiological thing or just when people start actually weighing themselves properly in c/tirzepatide · 14 points · 4 days ago
one person is not a study, one hundred people complaining about the same week on a forum is also not a study, but it is a pattern worth explaining somehow
comment on scale hasn’t moved in nine days, week 4, am I stalling already in c/semaglutide · 21 points · 4 days ago
should be a stickied graphic at this point
comment on net peptide content: i finally have a number and almost nothing to compare it against in c/scamalerts · 88 points · 4 days ago
4/4 on time from the warehouse, 6/9 direct. averaging those into a single number is almost misleading and i say that about this vendor more than any other.
comment on [Resolved] the QST batch dispute — vendor retested at their own cost, numbers matched, my error in c/scamalerts · -11 points · 4 days ago
one gracious vendor response does not offset a bad batch record
comment on [Medutest] SWB sema 10mg — 98.7%, and fourteen shipments with the cold chain intact in c/labresults · 61 points · 4 days ago
take it, i will never write anything that useful again
comment on went up a dose over a stall that turned out to be dehydration, learned an expensive lesson in c/maintenancephase · 12 points · 4 days ago
the "can't fully separate the variables" honesty at the end is worth more than a clean story would have been, real self-experimentation is usually this messy
comment on [Medutest] SWB sema 10mg — 98.7%, and fourteen shipments with the cold chain intact in c/labresults · 96 points · 5 days ago
which is also an argument for the rating being an average of a lot of different scar tissue rather than any one person's judgement.
comment on tapered slowly over four months instead of stopping cold, regain was 4kg not 24 in c/maintenancephase · 19 points · 7 days ago
one good data point on an under-studied question is worth posting even though it's not proof of anything at scale, glad this exists
comment on the week 8 version of this is different from the week 4 wall and I don’t think enough people separate them in c/maintenancephase · 6 points · 8 days ago
this thread and the noise-vs-plateau one should genuinely be linked together somewhere, they answer two halves of the same question
comment on the shortage thing finally clicked for me and I want to write it down in c/glp1aus · 16 points · 23 days ago
That is a pharmacy-level stock issue rather than a national supply issue. They feel identical and are not.
comment on identity and quantity are two questions and most COAs answer one in c/coa · 1 points · 1 months ago
Are the related substances itemised or is it a single total?
comment on help me understand purity, I have read the wiki twice in c/coa · 34 points · 1 months ago
Does the lot on the vial match the lot on the page?
comment on genuine question about area percent that I am slightly embarrassed to ask in c/coa · 1 points · 2 months ago
the counterion is part of the mass you paid for
comment on help me understand COA, I have read the wiki twice in c/coa · 82 points · 2 months ago
Net peptide content is the fraction of the powder that is actually peptide once counterion, water and residual solvent are accounted for. A 99% pure acetate salt can still be about 85% peptide by mass.
comment on the COA thing finally clicked for me and I want to write it down in c/coa · 18 points · 2 months ago
post the whole document, not the headline number
comment on [Lab] 18th independent test on HJ — 99.2% on a claimed 99.0%, and the trend is the interesting part in c/coa · 44 points · 3 months ago
chromatogram or it did not happen
comment on [PSA] purity is not what most of this community thinks it is in c/coa · 84 points · 4 months ago
Does the lot on the vial match the lot on the page?
comment on [Discussion] we are measuring purity at the wrong time and calling it noise in c/coa · 1 points · 4 months ago
Are the related substances itemised or is it a single total?
comment on [Discussion] we are measuring purity at the wrong time and calling it noise in c/coa · 26 points · 4 months ago
Asked KP for the batch-specific certificate and had the full document — batch, date, method line naming the column — inside six hours. That is now my baseline for everybody.
comment on area percent — 13 things I got wrong before I got it right in c/coa · 612 points · 5 months ago
The PDF creation date being later than the analysis date is usually a re-issue or a re-export. It is worth one question and it is not evidence of anything on its own.
comment on certificate of analysis — 18 things I got wrong before I got it right in c/coa · 60 points · 9 months ago
Agreed — the itemised related substances table is the difference between a document and a receipt.
comment on [Meta] proposal — a flair for related substances posts in c/coa · 13 points · 9 months ago
Correction: that is net peptide content, not purity. Different number, different meaning, and the document says so if you read the row label.
comment on [Discussion] TGA is doing more work than we give it credit for in c/glp1aus · 10 points · 1 year ago
say which state only if it matters, but always say which country
comment on purity — 6 things I got wrong before I got it right in c/coa · 119 points · 1 year ago
net peptide content and purity are two different numbers on the same vial
comment on Canada: Australia, and what it actually costs here in c/glp1aus · 122 points · 1 year ago
The compounded arrangements changed while I was mid-thread and I was arguing from a superseded position.