TRIUMPH

reading TRIUMPH threads from 2024 and half of it aged badly, which sounds obvious until you try to state the evidence for it. It is a triple agonist at the GLP-1, GIP…

proposal — a flair for phase 2 posts. Disagreement welcome, but bring a concrete alternative wording. Increases in heart rate have been reported across this receptor…

Asking properly rather than in a comment on somebody else’s thread: why does nobody talk about SELECT. Relative risk reduction without the baseline rate is…

26 weeks on 1.7mg, full numbers, ask me anything boring. Full detail below, and I have tried to keep the editorialising out of it. To save the first four comments: 26…

genuine question about retatrutide that I am slightly embarrassed to ask. Searched first, found three threads that contradict each other, hence the post. The thing that…

retatrutide is the most under-discussed thing on this board — a position I have arrived at slowly and would like tested. Phase 2 estimates effect and finds a dose…

is it normal to get sulphur burps at week 24. Full detail below, and I have tried to keep the editorialising out of it. The phase 2 readout ran to 48 weeks in a few…

why does nobody talk about SELECT. Searched first, found three threads that contradict each other, hence the post. Spent an evening with the appendix tables and found…

how much of what we believe about endpoint actually comes from TRIUMPH threads. I would rather ask a basic question now than get this wrong quietly for two months. A…

SURPASS — 12 things I got wrong before I got it right — a position I have arrived at slowly and would like tested. Relative risk reduction without the baseline rate is…

someone explain FLOW to me like I have not read a paper in years — that is what I am asking, and I have already read the wiki twice. Started keeping the trial…

the endpoint advice in here is 3 years out of date. It is the sort of thing everyone half-believes and nobody writes down. 3 years. Those are measured, not estimated,…

Check-in as promised in the title: 14 months in and retatrutide is still the thing I get wrong. 14 months — those are the numbers, and they are the ones I am willing to…

The title is the whole question — help me understand SURMOUNT, I have read the wiki twice — but here is why I am asking. Discontinuation rates are a tolerability…

endpoint — what am I missing here. I would rather ask a basic question now than get this wrong quietly for two months. Spent an evening with the appendix tables and…

how do you actually verify SURPASS. I would rather ask a basic question now than get this wrong quietly for two months. A confidence interval is the range of effects…

TRIUMPH is doing more work than we give it credit for. Making the case below, and I expect to lose some of it in the comments. Argued for a week about a result and then…

someone explain FLOW to me like I have not read a paper in years. Searched first, found three threads that contradict each other, hence the post. The discontinuation…

The title is the argument: the TRIUMPH thing finally clicked for me and I want to write it down. Here is the rest of it. Independent purity testing on this compound is…

week 21 check-in — 8kg down, fatigue manageable, one thing confusing me. Posting the boring middle of the process, because the internet is full of the start and the end…

the STEP question that gets asked weekly, answered properly. Not a hot take, just something I have not seen said plainly here. Spent an evening with the appendix tables…

two reta batches, two services, 98.4% and 97.9%, and before anyone asks: same batch throughout, single submission, no cherry-picking between services. 98.4% and 97.9%.…

Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about endpoint actually comes from SURMOUNT threads. Compared myself to…

The title is the whole question — does SELECT actually matter or is it forum lore at this point — but here is why I am asking. Went looking for the registered protocol…