glucagon

Posting this as a discussion rather than a claim: dose escalation — my 2-week log, condensed into one table. Phase 2 estimates effect and finds a dose range. Phase 3…

Posting this as a discussion rather than a claim: TRIUMPH — 16 things I got wrong before I got it right. What the glucagon arm is doing, as best anyone can say from…

the retatrutide question that gets asked weekly, answered properly. It is the sort of thing everyone half-believes and nobody writes down. Went up slowly, deliberately,…

anyone else notice glucagon kicking in around week 47. Full detail below, and I have tried to keep the editorialising out of it. Imaging-derived liver fat fraction is a…

came off reta after 14 weeks. here is the honest version. Not a hot take, just something I have not seen said plainly here. The relevant figures are 14 weeks, and they…

TRIUMPH: what the trials say vs what this community says. It is the sort of thing everyone half-believes and nobody writes down. Went up slowly, deliberately, because…

Six-word version is the title — small win: glucagon stopped being a problem at week 32 — and the rest is context. Went up slowly, deliberately, because everything on…

Six-word version is the title — 8 weeks on 7.5mg, full numbers, ask me anything boring — and the rest is context. Hard numbers: 8 weeks and 7.5mg. Anything softer than…

phase 2 — 18 things I got wrong before I got it right. Making the case below, and I expect to lose some of it in the comments. The phase 2 readout ran to 48 weeks in a…

Asking properly rather than in a comment on somebody else’s thread: help me understand triple agonist, I have read the wiki twice. Phase 2 estimates effect and finds a…

45 weeks on 10mg, full numbers, ask me anything boring, and the part I actually want to talk about is at the bottom. Pulling the figures out of the title: 45 weeks and…

49 weeks, 7kg, and dose escalation was the hard part. Numbers below. Ask me the boring questions, they are the useful ones. Numbers, in the order they matter: 49 weeks…

can we stop arguing about retatrutide until somebody posts a number, and I want the answer with the reasoning attached rather than just the conclusion. Where the…

the MASH thing finally clicked for me and I want to write it down, which sounds obvious until you try to state the evidence for it. Independent purity results for this…

how do you actually verify MASH. I would rather ask a basic question now than get this wrong quietly for two months. Read the phase 2 hepatic paper properly and the…

Slightly embarrassed to be asking this, but: genuine question about dual agonist that I am slightly embarrassed to ask. Imaging-derived liver fat fraction is a…

TRIUMPH is the most under-discussed thing on this board. Making the case below, and I expect to lose some of it in the comments. Stopped at a low step because there was…

Right: split one vial across Janoshik and Medutest — 99.2% and 98.9%. I paid for this one myself, nobody sent me anything, and the receipts are in the comments. Hard…

small win: MASH stopped being a problem at week 43. Full detail below, and I have tried to keep the editorialising out of it. Imaging-derived liver fat fraction is a…

what changed for me between month 8 and month 16, and I want the answer with the reasoning attached rather than just the conclusion. Sent a vial to Medutest out of…

week 62 check-in — 12kg down, fatigue manageable, one thing confusing me. Same spreadsheet I have been keeping since the start, nothing retrofitted. Pulling the figures…

dual agonist — 21 things I got wrong before I got it right, and I am aware this is a minority view on this board. What this compound is actually being developed for,…

Posting this as a discussion rather than a claim: hepatic fat — 19 things I got wrong before I got it right. Went slowly because everything published describes a…

how do you actually verify glucagon, and I want the answer with the reasoning attached rather than just the conclusion. Where the evidence actually stands, since every…

what changed for me between month 5 and month 8. I am not trying to be the "source?" guy. I would just like a source. Assumed the weight numbers were the point and was…