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c/tirzepatide·submitted 1 months ago by u/kaia_wojcik

[Discussion] we are measuring tirzepatide at the wrong time and calling it noise

Discussionbranch of 6 comments

we are measuring tirzepatide at the wrong time and calling it noise. Change my mind, genuinely — I have no stake in being right about this. Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and everything settled. Came off sema and onto tirz with a two-week gap. The…

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6 comments, started 1 months ago
u/zaid_balogun-22 points·1 months ago

Pen or vial? The step sizes available differ and it changes this answer.

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u/ingrid_correia1 point·1 months ago

Pen or vial?

Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.

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u/kian_ekstrom1 point·1 months ago

Correction to my own post above — I said 10mg and I have been on 12.5mg since the spring. Same argument, wrong number.

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u/emil_okwuosa1 point·1 months ago

sulphur burps are the signature complaint and they are not dangerous

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u/endpoint_creep1 point·1 months ago

What step are you on and how long have you been there?

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[deleted]1 point·1 months ago

[deleted]

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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