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c/tapering·submitted 1 months ago by u/maintenance_mode_max

[Results] 69 weeks, 24kg, and appetite return was the hard part

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69 weeks, 24kg, and appetite return was the hard part. Same spreadsheet I have been keeping since the start, nothing retrofitted. Numbers, in the order they matter: 69 weeks and 24kg. Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing. Had the…

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9 comments, started 1 months ago
u/malin_petrescu4 points·1 months ago

coming back later is allowed and it is common

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u/katrin_diallo-10 points·1 months ago

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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