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c/tapering·posted 1 months ago by u/maintenance_mode_max

[Results] 69 weeks, 24kg, and appetite return was the hard part

Results

69 weeks, 24kg, and appetite return was the hard part. Same spreadsheet I have been keeping since the start, nothing retrofitted.

Numbers, in the order they matter: 69 weeks and 24kg.

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

Had the conversation with a clinician before stopping rather than after. Considerably easier that way round.

If somebody has the same thing measured a different way, post it next to mine and we will see whether they agree.

39 up / 53 down42% upvoted11 commentsid 1ew2ul4 Jun 2026

11 comments

11 in this archive, depth 5

best — the order this archive was captured in

u/ahmed_okafor8 points·1 months ago

Nothing on this board is a taper schedule, and no member can write one for another. What can be shared is what people watched and what they observed.

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u/malin_petrescu4 points·1 months ago

coming back later is allowed and it is common

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u/katrin_diallo-10 points·1 months ago

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

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u/source_or_silence4 points·1 months ago

There is very little published guidance on stopping specifically, which is exactly why board consensus here should carry less weight than usual and a clinician conversation should carry more.

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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