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c/sideeffects·submitted 4 months ago by u/placebo_arm_pam

anyone else notice fatigue kicking in around week 46

Managementbranch of 6 comments

anyone else notice fatigue kicking in around week 46. Full detail below, and I have tried to keep the editorialising out of it. Constipation is mostly reduced intake plus reduced fluid, not a direct effect. That is why the boring fibre and water answer keeps working. The effect on gastric emptying is most pronounced…

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6 comments, started 4 months ago
u/gentle_correctionnice about it24 points·4 months ago

On buying things to fix side effects, which I did extensively and would not do again.

The interventions that changed anything for me were all behavioural and free: smaller meals, eating slower, stopping food a few hours before sleep, more fibre and considerably more water. The things I bought did nothing I could detect, and I was motivated to detect something.

The other lever, which people forget, is time at dose. Holding rather than stepping is a legitimate plan and it fixed my tolerance where nothing else did.

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u/priya_weiss8 points·4 months ago

On buying things to fix side effects, which I did extensively and would not do again.

This is the shape almost everybody here describes, and it is the single most reassuring thing in the thread.

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u/aurel_mwangi9 points·4 months ago

write down when it starts and stops, the pattern is the useful part

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u/step_therapy_s20 points·4 months ago

Small fix — the shedding follows the rate of weight loss, not the compound, and it is temporary.

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u/placebo_arm_pamOP16 points·4 months ago

smaller meals, earlier, is the boring advice that works

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u/peptidemeter_pat8 points·4 months ago

if it is severe or persistent that is a clinician question, not a board question

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