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c/semaglutide·posted 1 year ago by u/gustav_solberg

[Results] 58 weeks, 21kg, and plateau was the hard part

Results Clean Column ×3 Long Haul ×2 Sourced ×1

Update, and the title has the headline: 58 weeks, 21kg, and plateau was the hard part.

58 weeks and 21kg. Those are measured, not estimated, and not rounded up in my favour.

What I would tell week-one me, in order of how much time it would have saved.

One: the first month is a tolerance check. You are finding out whether you can take this, not how much you will lose. Two: write down the dose, the day and the waist measurement. Three: a stall of under six weeks is weather, not climate. Four: reflux that arrives the day after the shot and fades by day four is the ordinary pattern and it usually settles at a stable dose.

None of that is advice about what you should do. It is the shape of the thing, which nobody explained to me and which the wiki explains better than I just did.

nausea made the first fortnight rough at each step up, then flattened out. Predictable enough that I started planning around it.

Tell me where this is wrong. That is the useful part of posting it.

11,821 up / 503 down96% upvoted52 commentsid 9uac7o29 Aug 2024

52 comments

23 in this archive, depth 5

best — the order this archive was captured in

u/camila_mensa-10 points·1 year ago

Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the early fullness usually fades at a stable dose.

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u/marit_coelho1 point·1 year ago

Week 19: 8kg down, constipation basically gone since about week 9, and the honest headline is that nothing dramatic happened. It was boring and it worked.

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u/gustav_solbergOP1 point·1 year ago

stalling at 1.0mg is information, not a verdict

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u/nadia_bakker1 point·1 year ago

the ladder exists because the gut needs the time, not because the pharmacy likes paperwork

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[removed]1 point·1 year ago

[removed by moderator]

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u/oskar_kaufmann1 point·1 year ago·edited

Minor fix — the half-life is about a week, not about a day. The rest of your point stands.

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u/hassan_ostergaard1 point·1 year ago·edited

Minor fix — the half-life is about a week, not about a day.

Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.

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u/reflux_report1 point·1 year ago

Sceptical of the mechanism you are proposing. Gastric emptying slows, it does not stop, and the timings you describe do not follow from it.

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u/gradient_goblin1 point·1 year ago

the food noise going quiet is the effect people actually describe

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u/leila_vasquez1.4k points·1 year ago

Careful. A four-week stall is inside normal variation and treating it as failure is how people escalate for no reason.

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u/quiet_moderatormod918 points·1 year ago·edited

The appetite thing was the surprise. I expected to feel full. What I got was simply not thinking about food between meals.

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u/runa_wikstrom504 points·1 year ago

That figure is the 68-week trial mean, not a weekly rate. Dividing it by the weeks gives you a number that does not mean anything.

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u/ffmi_watcher310 points·1 year ago

do not chase somebody else’s titration schedule, they are not you

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u/rina_bergstrom0 points·1 year ago

The appetite thing was the surprise.

Adding one thing to this: the appetite effect and the scale run on separate clocks, so both halves can be true at once.

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u/leila_silva914 points·1 year ago

My stall was eleven weeks. Eleven. Then it moved again without me changing anything at all.

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u/units_not_mgMOD651 points·1 year ago

Retitled to match the body. The original promised a comparison the post does not make.

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u/noor_hovland0 points·1 year ago

Retitled to match the body.

Disagree with this specific line. A pause at 1.7mg is not evidence that 1.7mg has stopped working.

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u/customs_seizure_sid0 points·1 year ago

Not convinced. You changed the dose and the week at the same time, so you cannot attribute the change to either.

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u/gustav_solbergOP1 point·1 year ago

What did week 28 look like compared with this one? The month either side is the useful comparison.

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u/rania_diallo1 point·1 year ago

First month I lost almost nothing and nearly quit. Month two and three were where it all happened.

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u/two_mil_or_one1 point·1 year ago

the scale is the least sensitive instrument you own

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u/camila_sandvik705 points·1 year ago

Weight change and appetite change are different endpoints on different timescales. Conflating them is where most of the confusion on this board starts.

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u/alcohol_aversion366 points·1 year ago·edited

Dropped my injection day by two days once because of travel. Nothing happened. The panic was worse than the effect.

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