[Results] 58 weeks, 21kg, and plateau was the hard part
Update, and the title has the headline: 58 weeks, 21kg, and plateau was the hard part. 58 weeks and 21kg. Those are measured, not estimated, and not rounded up in my favour. What I would tell week-one me, in order of how much time it would have saved. One: the first month is a tolerance check. You are finding out…
Delayed gastric emptying is most pronounced early and attenuates with continued dosing, which is why the early fullness usually fades at a stable dose.
Week 19: 8kg down, constipation basically gone since about week 9, and the honest headline is that nothing dramatic happened. It was boring and it worked.
stalling at 1.0mg is information, not a verdict
the ladder exists because the gut needs the time, not because the pharmacy likes paperwork
Minor fix — the half-life is about a week, not about a day. The rest of your point stands.
Minor fix — the half-life is about a week, not about a day.
Right, and the timescale is the bit that keeps getting lost. Judge a step at a month, not at a weekend.
Sceptical of the mechanism you are proposing. Gastric emptying slows, it does not stop, and the timings you describe do not follow from it.
the food noise going quiet is the effect people actually describe