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c/reconstitution·submitted 11 months ago by u/elin_ferrari

[Meta] proposal — a flair for dead space posts

PSAbranch of 15 comments

proposal — a flair for dead space posts. This affects how posts get sorted and removed, so it belongs in the open. Reconstituted at 3mL when I meant to use a different volume. Caught it because the units looked wrong on the barrel. Now I write 6.67mg/mL on the glass before I put the cap back. If your calculation…

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15 comments, started 11 months ago
u/emil_wojcik366 points·11 months ago

Agreed on the swirl. There is no reason to shake it and a good reason not to.

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u/elin_ferrariOP529 points·11 months ago

I keep a laminated card in the drawer with the arithmetic on it. Looks ridiculous. Has never once let me draw the wrong volume.

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u/elin_ferrariOP-32 points·11 months ago

bacteriostatic water has the preservative, sterile water does not

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u/janek_ferrari1 point·11 months ago

more water is not more drug, it is the same drug in a bigger volume

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u/nadia_kjaer123 points·11 months ago

if the maths gives you a fraction of a unit, change the concentration

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u/hedda_adeyemi61 points·11 months ago·edited

if the maths gives you a fraction of a unit, change the concentration

Right, and the arithmetic behind it: 5mg in 3mL is 1.67mg/mL, so 1mg is 60 units.

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u/ilias_cabrera51 points·11 months ago

Asked WWB what volume they reconstitute to for their own stability testing and they answered in one line. Useful thing to know.

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u/oskar_ibarra0 points·11 months ago

Asked WWB what volume they reconstitute to for their own stability testing and they answered in one line.

ilias_cabrera has the units point exactly right. They are a volume on the barrel and nothing else.

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u/nadia_kjaer1 point·11 months ago

ilias_cabrera has the units point exactly right.

This is the sentence that makes the rest unnecessary. Write it on the vial and the problem is gone.

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u/india_generic_g13 points·11 months ago

reconstituting at a round concentration makes every later dose easy

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u/vito_beaulieu0 points·11 months ago

Agreed on the swirl.

Adding one thing — put the date on the label too. Concentration plus date and you can never mix two vials up.

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u/katrin_marchetti1 point·11 months ago

Small fix — a U-100 syringe is 100 units per mL. If yours is marked differently it is not U-100 and the whole calculation changes.

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u/rosa_mensah1 point·11 months ago·edited

Wrote the date on the vial as well as the concentration after losing track of which one was opened first.

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u/batch_number_bertievetting1 point·11 months ago

The dead space question sent me down a rabbit hole for a week. It is a fraction of a unit and it is the same every draw.

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u/vial_math_verasyringe math1 point·11 months ago

a U-100 syringe reads 100 units to the millilitre, every time

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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