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c/reconstitution·submitted 1 year ago by u/ilias_cabrera

[Discussion] can we stop arguing about reconstitution until somebody posts a number

Discussionbranch of 13 comments

can we stop arguing about reconstitution until somebody posts a number — that is what I am asking, and I have already read the wiki twice. The failure modes I have actually seen posted here, in order of frequency. One: reconstituting at a different volume than intended and not writing it down, so the next draw is…

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13 comments, started 1 year ago
u/units_not_mgMOD115 points·1 year ago

Working has to be shown on arithmetic posts. Added a note asking for it rather than removing this one.

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u/anjali_tamm73 points·1 year ago·edited

Working has to be shown on arithmetic posts.

units_not_mg has the units point exactly right. They are a volume on the barrel and nothing else.

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u/escrow_evangelist93 points·1 year ago

Aim the stream down the wall of the vial rather than into the cake. Reconstitution is a solubility problem, not a mixing problem, and mechanical shear does nothing helpful.

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u/reflux_report52 points·1 year ago

Correction: that gives 25 units, not what you have written. 20mg into 2mL is 10mg/mL and the division follows from there.

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u/aleksi_lehtinen169 points·1 year ago

if the maths gives you a fraction of a unit, change the concentration

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u/ines_lindqvist103 points·1 year ago

Is that a U-100 syringe? The barrel markings change the answer completely.

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u/hedda_ekstrom42 points·1 year ago

This. Showing the working is the fastest way for somebody else to spot the mistake.

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u/ilias_cabreraOP62 points·1 year ago

Did the maths give you a whole number of units, or a fraction?

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u/gradient_goblin15 points·1 year ago

Spent 19 weeks confused about this until somebody drew the table for me. 5mg, 1mL, 5mg/mL, 5mg is 100 units. That is the whole thing.

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u/reflux_report0 points·1 year ago

What is written on the vial right now?

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u/sigrid_kaufmann0 points·1 year ago·edited

Reconstituted at 3mL when I meant to use a different volume. Caught it because the units looked wrong on the barrel. Now I write 6.67mg/mL on the glass before I put the cap back.

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u/julia_erdogan1 point·1 year ago

the number you write down is the number you will trust at 6am

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u/tuva_kirchner1 point·1 year ago

Show the arithmetic — where did the unit figure come from?

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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