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c/coldchain·submitted 11 months ago by u/kian_ekstrom

[PSA] stability is not what most of this community thinks it is

PSAbranch of 12 comments

stability is not what most of this community thinks it is. If you already knew this, the post is not for you and you can scroll on. Put a logger in three consecutive orders. Two never went above the range at all and the third spent four hours warm on a Friday. Cost me almost nothing to stop wondering. Gel pack fully…

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This branch

12 comments, started 11 months ago
u/ms_fragmenter311 points·11 months ago

light matters more than people think for some of these

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u/kian_ekstromOP152 points·11 months ago

What was the packaging — rigid outer, gel packs, anything insulating?

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u/kian_ekstromOP230 points·11 months ago

write the reconstitution date on the vial

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u/maren_sorensen103 points·11 months ago

write the reconstitution date on the vial

This is the distinction that resolves most threads here — powder and solution are different problems.

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u/jarno_karlsen77 points·11 months ago

Is this a line they hold in regional stock or is it shipping from origin?

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u/emil_marchand32 points·11 months ago

A transit temperature logger records a distribution, and time above a threshold matters as much as peak temperature. That is the argument for logging rather than guessing.

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u/ferran_laurent-29 points·11 months ago

Ordered from the warehouse in the Netherlands instead of origin and the transit went from a fortnight to 4 days. Entirely different proposition in August.

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u/transit_variance248 points·11 months ago

You cannot infer potency from a temperature record. The record tells you what happened to the box; only a test tells you what happened to the material.

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u/priya_guerrero357 points·11 months ago

Asked SSA which lines they hold regionally and got a straight list back. That answered my summer ordering question completely.

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u/ines_lindqvist520 points·11 months ago

Split an order across two months deliberately to compare summer and winter transit on the same lane. Four days difference, same carrier.

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u/ireland_drugs_pay320 points·11 months ago·edited

Split an order across two months deliberately to compare summer and winter transit on the same lane.

Disagreeing with this line only: freezing a reconstituted vial is not a safe default.

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u/runa_wikstrom214 points·11 months ago·edited

Correction: that stability figure covers the lyophilised powder, not the reconstituted solution. Different claim entirely.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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